MTMR6 Antibody, HRP conjugated (PACO42847)
- SKU:
- PACO42847
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | MTMR6 Antibody, HRP conjugated (PACO42847) |
抗体コード: | PACO42847 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Myotubularin-related protein 6 protein (1-260AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Phosphatase that acts on lipids with a phosphoinositol headgroup. Acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol 3 phosphatase. Negatively regulates proliferation of reactivated CD4+ T-cells. |
シノニム: | Myotubularin-related protein 6 (EC 3.1.3.-), MTMR6 |
UniProt Protein Function: | MTMR6: Phosphatase that acts on lipids with a phosphoinositol headgroup. Acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol 3 phosphatase. Negatively regulates proliferation of reactivated CD4+ T-cells. Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Protein phosphatase, tyrosine (non-receptor); EC 3.1.3.-; Cofactor and Vitamin Metabolism - riboflavin; Phosphatase, lipid; Cofactor and Vitamin Metabolism - thiamine; Carbohydrate Metabolism - fructose and mannose Chromosomal Location of Human Ortholog: 13q12 Cellular Component: cytoplasm; cytosol Molecular Function:calcium-activated potassium channel activity; phosphatidylinositol-3-phosphatase activity; protein binding Biological Process: phosphatidylinositol biosynthetic process |
UniProt Code: | Q9Y217 |
NCBI GenInfo Identifier: | 317373414 |
NCBI Gene ID: | 9107 |
NCBI Accession: | Q9Y217.3 |
UniProt Secondary Accession: | Q9Y217,Q5JRG6, Q86TB7, Q86YH4, Q96P80, B2RBB5, B3KSB4 |
UniProt Related Accession: | Q9Y217 |
Molecular Weight: | 63,743 Da |
NCBI Full Name: | Myotubularin-related protein 6 |
NCBI Synonym Full Names: | myotubularin related protein 6 |
NCBI Official Symbol: | MTMR6 |
NCBI Protein Information: | myotubularin-related protein 6 |
UniProt Protein Name: | Myotubularin-related protein 6 |
Protein Family: | Myotubularin-related protein |
UniProt Gene Name: | MTMR6 |
UniProt Entry Name: | MTMR6_HUMAN |