MTMR3 Antibody, HRP conjugated (PACO62744)
- SKU:
- PACO62744
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | MTMR3 Antibody, HRP conjugated (PACO62744) |
抗体コード: | PACO62744 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Myotubularin-related protein 3 protein (652-899AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate. May also dephosphorylate proteins phosphorylated on Ser, Thr, and Tyr residues. |
シノニム: | Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64) (Zinc finger FYVE domain-containing protein 10), MTMR3, KIAA0371 ZFYVE10 |
UniProt Protein Function: | MTMR3: Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate. May also dephosphorylate proteins phosphorylated on Ser, Thr, and Tyr residues. Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 3.1.3.48; EC 3.1.3.64; EC 3.1.3.95; Motility/polarity/chemotaxis; Protein phosphatase, dual-specificity Chromosomal Location of Human Ortholog: 22q12.2 Cellular Component: cytoplasm; cytosol; extrinsic to membrane; membrane Molecular Function:phosphatidylinositol-3-phosphatase activity; protein binding; protein serine/threonine phosphatase activity; protein tyrosine phosphatase activity Biological Process: cellular response to glucose starvation; macroautophagy; phosphatidylinositol biosynthetic process; phosphoinositide dephosphorylation; protein amino acid dephosphorylation |
NCBI Summary: | This gene encodes a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein is structurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain. The protein can self-associate and also form heteromers with another myotubularin related protein. The protein binds to phosphoinositide lipids through the PH-GRAM domain, and can hydrolyze phosphatidylinositol(3)-phosphate and phosphatidylinositol(3,5)-biphosphate in vitro. The encoded protein has been observed to have a perinuclear, possibly membrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q13615 |
NCBI GenInfo Identifier: | 33112668 |
NCBI Gene ID: | 8897 |
NCBI Accession: | Q13615.3 |
UniProt Secondary Accession: | Q13615,Q9NYN5, Q9NYN6, Q9UDX6, Q9UEG3, A5PL26, A7MD32 |
UniProt Related Accession: | Q13615 |
Molecular Weight: | 134kDa |
NCBI Full Name: | Myotubularin-related protein 3 |
NCBI Synonym Full Names: | myotubularin related protein 3 |
NCBI Official Symbol: | MTMR3 |
NCBI Official Synonym Symbols: | ZFYVE10; FYVE-DSP1 |
NCBI Protein Information: | myotubularin-related protein 3 |
UniProt Protein Name: | Myotubularin-related protein 3 |
UniProt Synonym Protein Names: | FYVE domain-containing dual specificity protein phosphatase 1; FYVE-DSP1; Phosphatidylinositol-3,5-bisphosphate 3-phosphatase (EC:3.1.3.95 |
UniProt Gene Name: | MTMR3 |