MT-ND6 Antibody (PACO20047)
- SKU:
- PACO20047
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| 抗体名: | MT-ND6 Antibody (PACO20047) |
| 抗体コード: | PACO20047 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, IHC |
| 推奨される希釈: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
| 反応性: | Human |
| 免疫原: | Synthetic peptide of human MT-ND6 |
| 憲法: | Liquid |
| ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 精製方法: | Antigen affinity purification |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO20047(MT-ND6 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO20047(MT-ND6 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
| バックグラウンド: | NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by translocation of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. The significance of NADH dehydrogenase subunit 6 (ND6) is rapidly becoming increasingly apparent as many mutations leading to amino acid, changes in this subunit are associated with known mitochondrial diseases. |
| シノニム: | mitochondrially encoded NADH dehydrogenase 6 |
| UniProt Protein Function: | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
| UniProt Code: | P03923 |
| NCBI GenInfo Identifier: | 6648060 |
| NCBI Gene ID: | 4541 |
| NCBI Accession: | P03923.2 |
| UniProt Secondary Accession: | P03923,Q34774, Q8HG30, |
| UniProt Related Accession: | P03923 |
| Molecular Weight: | 18,622 Da |
| NCBI Full Name: | NADH-ubiquinone oxidoreductase chain 6 |
| NCBI Synonym Full Names: | mitochondrially encoded NADH dehydrogenase 6 |
| NCBI Official Symbol: | MT-ND6 |
| NCBI Official Synonym Symbols: | MTND6; ND6 |
| NCBI Protein Information: | NADH dehydrogenase, subunit 6 (complex I) |
| UniProt Protein Name: | NADH-ubiquinone oxidoreductase chain 6 |
| UniProt Synonym Protein Names: | NADH dehydrogenase subunit 6 |
| UniProt Gene Name: | MT-ND6 |
| Antibodies |
| Anti-MT-ND6 Antibody (CAB17991) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |