MT-ND3 Antibody (PACO20050)
- SKU:
- PACO20050
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | MT-ND3 Antibody (PACO20050) |
抗体コード: | PACO20050 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
反応性: | Human |
免疫原: | Synthetic peptide of human MT-ND3 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO20050(MT-ND3 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO20050(MT-ND3 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by trans-location of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 3 (ND3) localizes to the hydrophobic protein fragment of complex I. Mutations in the gene encodiing for ND3 may be associated with Parkinson disease. |
シノニム: | mitochondrially encoded NADH dehydrogenase 3 |
UniProt Protein Function: | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
UniProt Code: | P03897 |
NCBI GenInfo Identifier: | 128710 |
NCBI Gene ID: | 4537 |
NCBI Accession: | P03897.1 |
UniProt Related Accession: | P03897 |
Molecular Weight: | 13,186 Da |
NCBI Full Name: | NADH-ubiquinone oxidoreductase chain 3 |
NCBI Synonym Full Names: | mitochondrially encoded NADH dehydrogenase 3 |
NCBI Official Symbol: | MT-ND3 |
NCBI Official Synonym Symbols: | MTND3; ND3 |
NCBI Protein Information: | NADH dehydrogenase, subunit 3 (complex I) |
UniProt Protein Name: | NADH-ubiquinone oxidoreductase chain 3 |
UniProt Synonym Protein Names: | NADH dehydrogenase subunit 3 |
UniProt Gene Name: | MT-ND3 |
Antibodies |
Anti-MT-ND3 Antibody (CAB17969) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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