MSLN Antibody, FITC conjugated (PACO32826)
- SKU:
- PACO32826
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | MSLN Antibody, FITC conjugated (PACO32826) |
抗体コード: | PACO32826 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Mesothelin protein (37-598AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Membrane-anchored forms may play a role in cellular adhesion. Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro. |
シノニム: | Mesothelin (CAK1 antigen) (Pre-pro-megakaryocyte-potentiating factor) [Cleaved into: Megakaryocyte-potentiating factor (MPF); Mesothelin, cleaved form], MSLN, MPF |
UniProt Protein Function: | MSLN: Membrane-anchored forms may play a role in cellular adhesion. Antibodies against MSLN are detected in patients with mesothelioma and ovarian cancer. Belongs to the mesothelin family. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, GPI anchor; Cell adhesion Chromosomal Location of Human Ortholog: 16p13.3 Cellular Component: Golgi apparatus; extracellular space; cell surface; membrane; plasma membrane Molecular Function:protein binding Biological Process: pancreas development; cell adhesion |
NCBI Summary: | This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010] |
UniProt Code: | Q13421 |
NCBI GenInfo Identifier: | 116242654 |
NCBI Gene ID: | 10232 |
NCBI Accession: | Q13421.2 |
UniProt Secondary Accession: | Q13421,Q14859, Q4VQD5, Q96GR6, Q96KJ5, Q9BR17, Q9BTR2 Q9UCB2, Q9UK57, D3DU65, |
UniProt Related Accession: | Q13421 |
Molecular Weight: | 67,940 Da |
NCBI Full Name: | Mesothelin |
NCBI Synonym Full Names: | mesothelin |
NCBI Official Symbol: | MSLN |
NCBI Official Synonym Symbols: | MPF; SMRP |
NCBI Protein Information: | mesothelin; CAK1 antigen; megakaryocyte potentiating factor; soluble MPF mesothelin related protein; pre-pro-megakaryocyte-potentiating factor |
UniProt Protein Name: | Mesothelin |
UniProt Synonym Protein Names: | CAK1 antigen; Pre-pro-megakaryocyte-potentiating factorCleaved into the following 2 chains:Megakaryocyte-potentiating factor; MPF; Mesothelin, cleaved form |
Protein Family: | Mesothelin |
UniProt Gene Name: | MSLN |
UniProt Entry Name: | MSLN_HUMAN |