Ms4a1 Antibody, Biotin conjugated (PACO28397)
- SKU:
- PACO28397
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | Ms4a1 Antibody, Biotin conjugated (PACO28397) |
抗体コード: | PACO28397 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Mouse |
免疫原: | Recombinant Mouse B-lymphocyte antigen CD20 protein (111-291AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | This protein may be involved in the regulation of B-cell activation and proliferation. |
シノニム: | B-lymphocyte antigen CD20 (B-cell differentiation antigen Ly-44) (Lymphocyte antigen 44) (Membrane-spanning 4-domains subfamily A member 1) (CD antigen CD20), Ms4a1, Cd20 Ly-44 Ms4a2 |
UniProt Protein Function: | MS4A1: This protein may be involved in the regulation of B-cell activation and proliferation. Defects in MS4A1 are the cause of immunodeficiency common variable type 5 (CVID5); also called antibody deficiency due to CD20 defect. CVID5 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells is usually in the normal range, but can be low. Belongs to the MS4A family.Protein type: Cell surface; Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 19 A|19 8.19 cMCellular Component: external side of plasma membrane; extracellular exosome; extracellular space; integral component of membrane; integral component of plasma membrane; membrane; plasma membraneMolecular Function: epidermal growth factor receptor binding; protein bindingBiological Process: B cell activation |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | P19437 |
NCBI GenInfo Identifier: | 6671710 |
NCBI Gene ID: | 12482 |
NCBI Accession: | NP_031667.1 |
UniProt Secondary Accession: | P19437 |
UniProt Related Accession: | P19437 |
Molecular Weight: | 31,958 Da |
NCBI Full Name: | B-lymphocyte antigen CD20 |
NCBI Synonym Full Names: | membrane-spanning 4-domains, subfamily A, member 1 |
NCBI Official Symbol: | Ms4a1 |
NCBI Official Synonym Symbols: | Cd20; Ly-44; Ms4a2; AA960661 |
NCBI Protein Information: | B-lymphocyte antigen CD20 |
UniProt Protein Name: | B-lymphocyte antigen CD20 |
UniProt Synonym Protein Names: | B-cell differentiation antigen Ly-44; Lymphocyte antigen 44; Membrane-spanning 4-domains subfamily A member 1; CD_antigen: CD20 |
Protein Family: | CD209 antigen |
UniProt Gene Name: | Ms4a1 |
UniProt Entry Name: |