MOV10 Antibody (PACO40458)
- SKU:
- PACO40458
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | MOV10 Antibody (PACO40458) |
抗体コード: | PACO40458 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Putative helicase MOV-10 protein (601-900AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: MOV10 antibody at 0.4µg/ml. Lane 1: HepG2 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 114, 102, 7 kDa. Observed band size: 114 kDa. | |
Immunohistochemistry of paraffin-embedded human testis tissue using PACO40458 at dilution of 1:100. |
バックグラウンド: | Probable RNA helicase. Required for RNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC. Also required for RNA-directed transcription and replication of the human hepatitis delta virus (HDV). Interacts with small capped HDV RNAs derived from genomic hairpin structures that mark the initiation sites of RNA-dependent HDV RNA transcription. |
シノニム: | Putative helicase MOV-10 (EC 3.6.4.13) (Armitage homolog) (Moloney leukemia virus 10 protein), MOV10, KIAA1631 |
UniProt Protein Function: | MOV10: Probable RNA helicase. Required for RNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA- mediated cleavage of complementary mRNAs by RISC. Also required for RNA-directed transcription and replication of the human hepatitis delta virus (HDV). Interacts with small capped HDV RNAs derived from genomic hairpin structures that mark the initiation sites of RNA-dependent HDV RNA transcription. Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:RNA-binding; RNA processing; Helicase; EC 3.6.4.13; Spliceosome Chromosomal Location of Human Ortholog: 1p13.2 Cellular Component: extracellular space; cytosol Molecular Function:protein binding; helicase activity; ATP binding Biological Process: epidermal growth factor receptor signaling pathway; Notch signaling pathway; fibroblast growth factor receptor signaling pathway; phosphoinositide-mediated signaling; transcription, DNA-dependent; regulation of transcription, DNA-dependent; nerve growth factor receptor signaling pathway; miRNA-mediated gene silencing, mRNA cleavage; innate immune response |
UniProt Code: | Q9HCE1 |
NCBI GenInfo Identifier: | 24638063 |
NCBI Gene ID: | 4343 |
NCBI Accession: | Q9HCE1.2 |
UniProt Related Accession: | Q9HCE1 |
Molecular Weight: | |
NCBI Full Name: | Helicase MOV-10 |
NCBI Synonym Full Names: | Mov10 RISC complex RNA helicase |
NCBI Official Symbol: | MOV10 |
NCBI Official Synonym Symbols: | gb110; fSAP113 |
NCBI Protein Information: | helicase MOV-10; putative helicase MOV-10 |
UniProt Protein Name: | Putative helicase MOV-10 |
UniProt Synonym Protein Names: | Moloney leukemia virus 10 protein |
Protein Family: | Putative helicase |
UniProt Gene Name: | MOV10 |
UniProt Entry Name: | MOV10_HUMAN |