MORC2 Antibody, HRP conjugated (PACO42647)
- SKU:
- PACO42647
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | MORC2 Antibody, HRP conjugated (PACO42647) |
抗体コード: | PACO42647 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human MORC family CW-type zinc finger protein 2 protein (2-300AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Exhibits a cytosolic function in lipogenesis, adipogenic differentiation, and lipid homeostasis by increasing the activity of ACLY, possibly preventing its dephosphorylation. May act as a transcriptional repressor. Down-regulates CA9 expression. |
シノニム: | MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled-coil domain protein 1), MORC2, KIAA0852 ZCWCC1 |
UniProt Protein Function: | MORC2: a protein containing a Zinc finger CW-type coiled-coil domain and a HATPase_c domain. HATPase_c domains are found in several ATP-binding proteins including histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, and DNA mismatch repair proteins. |
UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 22q12.2 Cellular Component: cytoplasm; nucleus |
NCBI Summary: | This gene encodes a member of the Microrchidia (MORC) protein superfamily. The encoded protein is known to regulate the condensation of heterochromatin in response to DNA damage and play a role in repressing transcription. The protein has been found to regulate the activity of ATP citrate lyase via specific interaction with this enzyme in the cytosol of lipogenic breast cancer cells. The protein also plays a role in lipogenesis and adipocyte differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016] |
UniProt Code: | Q9Y6X9 |
NCBI GenInfo Identifier: | 114152840 |
NCBI Gene ID: | 22880 |
NCBI Accession: | Q9Y6X9.2 |
UniProt Secondary Accession: | Q9Y6X9,Q9UF28, Q9Y6V2, B2RNB1, |
UniProt Related Accession: | Q9Y6X9 |
Molecular Weight: | 110,724 Da |
NCBI Full Name: | MORC family CW-type zinc finger protein 2 |
NCBI Synonym Full Names: | MORC family CW-type zinc finger 2 |
NCBI Official Symbol: | MORC2 |
NCBI Official Synonym Symbols: | ZCW3; CMT2Z; ZCWCC1 |
NCBI Protein Information: | MORC family CW-type zinc finger protein 2 |
UniProt Protein Name: | MORC family CW-type zinc finger protein 2 |
UniProt Synonym Protein Names: | Zinc finger CW-type coiled-coil domain protein 1 |
Protein Family: | MORC family CW-type zinc finger protein |
UniProt Gene Name: | MORC2 |
UniProt Entry Name: | MORC2_HUMAN |