MOK Antibody (PACO21202)
- SKU:
- PACO21202
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | MOK Antibody (PACO21202) |
抗体コード: | PACO21202 |
サイズ: | 100ul(100ug) |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:50-1:200 |
反応性: | Human, Mouse, Rat |
免疫原: | Recombinant protein of human RAGE |
憲法: | Liquid |
ストレージバッファ: | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of extracts of mouse liver cell lines, using RAGE antibody. |
バックグラウンド: | This gene belongs to the MAP kinase superfamily. The gene was found to be regulated by caudal type transcription factor 2 (Cdx2) protein. The encoded protein, which is localized to epithelial cells in the intestinal crypt, may play a role in growth arrest and differentiation of cells of upper crypt and lower villus regions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene. |
シノニム: | MOK; RAGE; RAGE-1; RAGE1 |
UniProt Protein Function: | MOK: a CMGC protein kinase of the RCK family. Possesses a Thr-Glu-Tyr motif in the activation loop domain, as do classical MAP kinases. Associates with and is apparently stabilized by HSP90. |
UniProt Protein Details: | Protein type:Kinase, protein; Protein kinase, CMGC; EC 2.7.11.22; Protein kinase, Ser/Thr (non-receptor); CMGC group; RCK family Chromosomal Location of Human Ortholog: 14q32 Cellular Component: cytoplasm Molecular Function:protein serine/threonine kinase activity; cyclin-dependent protein kinase activity; ATP binding; protein kinase activity Biological Process: regulation of cell cycle; signal transduction; protein amino acid phosphorylation |
NCBI Summary: | This gene belongs to the MAP kinase superfamily. The gene was found to be regulated by caudal type transcription factor 2 (Cdx2) protein. The encoded protein, which is localized to epithelial cells in the intestinal crypt, may play a role in growth arrest and differentiation of cells of upper crypt and lower villus regions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Dec 2012] |
UniProt Code: | Q9UQ07 |
NCBI GenInfo Identifier: | 41017258 |
NCBI Gene ID: | 5891 |
NCBI Accession: | Q9UQ07.1 |
UniProt Secondary Accession: | Q9UQ07,Q92790, Q93067, B2R6Z4, B7Z7P6, E7ER76, E7ERR8 |
UniProt Related Accession: | Q9UQ07 |
Molecular Weight: | 419 |
NCBI Full Name: | MAPK/MAK/MRK overlapping kinase |
NCBI Synonym Full Names: | MOK protein kinase |
NCBI Official Symbol: | MOK |
NCBI Official Synonym Symbols: | RAGE; RAGE1; STK30; RAGE-1 |
NCBI Protein Information: | MAPK/MAK/MRK overlapping kinase; renal tumor antigen 1; renal cell carcinoma antigen |
UniProt Protein Name: | MAPK/MAK/MRK overlapping kinase |
UniProt Synonym Protein Names: | MOK protein kinase; Renal tumor antigen 1; RAGE-1 |
Protein Family: | MAPK/MAK/MRK overlapping kinase |
UniProt Gene Name: | MOK |
UniProt Entry Name: | MOK_HUMAN |