MMP10 Antibody (PACO04345)
- SKU:
- PACO04345
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | MMP10 Antibody |
抗体コード: | PACO04345 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC, IF |
推奨される希釈: | IHC:1:100-1:300, IF:1:200-1:1000 |
反応性: | Human, Mouse, Rat |
免疫原: | synthesized peptide derived from the C-terminal region of human MMP-10. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | MMP10; STMY2; Stromelysin-2; SL-2; Matrix metalloproteinase-10; MMP-10; Transin-2 |
UniProt Protein Function: | MMP10: Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase. Belongs to the peptidase M10A family. |
UniProt Protein Details: | Protein type:EC 3.4.24.22; Secreted; Protease; Extracellular matrix; Secreted, signal peptide Chromosomal Location of Human Ortholog: 11q22.3 Cellular Component: extracellular space; proteinaceous extracellular matrix; extracellular region Molecular Function:zinc ion binding; metalloendopeptidase activity; calcium ion binding Biological Process: collagen catabolic process; extracellular matrix disassembly; extracellular matrix organization and biogenesis; proteolysis; regulation of cell migration |
NCBI Summary: | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008] |
UniProt Code: | P09238 |
NCBI GenInfo Identifier: | 116869 |
NCBI Gene ID: | 4319 |
NCBI Accession: | P09238.1 |
UniProt Secondary Accession: | P09238,Q53HH9, B2R9X9, |
UniProt Related Accession: | P09238 |
Molecular Weight: | 476 |
NCBI Full Name: | Stromelysin-2 |
NCBI Synonym Full Names: | matrix metallopeptidase 10 (stromelysin 2) |
NCBI Official Symbol: | MMP10 |
NCBI Official Synonym Symbols: | SL-2; STMY2 |
NCBI Protein Information: | stromelysin-2; MMP-10; transin 2; transin-2; stromelysin 2; matrix metalloprotease 10; matrix metalloproteinase-10; matrix metalloproteinase 10 (stromelysin 2) |
UniProt Protein Name: | Stromelysin-2 |
UniProt Synonym Protein Names: | Matrix metalloproteinase-10; MMP-10; Transin-2 |
Protein Family: | Stromelysin |
UniProt Gene Name: | MMP10 |
UniProt Entry Name: | MMP10_HUMAN |