MIEF1 Antibody, FITC conjugated (PACO41160)
- SKU:
- PACO41160
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | MIEF1 Antibody, FITC conjugated (PACO41160) |
抗体コード: | PACO41160 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Mitochondrial dynamics protein MID51 protein (51-309AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, although with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP. Inhibits DNM1L GTPase activity in the absence of bound ADP. Requires ADP to stimulate DNM1L GTPase activity and the assembly of DNM1L into long, oligomeric tubules with a spiral pattern, as opposed to the ring-like DNM1L oligomers observed in the absence of bound ADP. Does not require ADP for its function in recruiting DNM1L. |
シノニム: | Mitochondrial dynamics protein MID51 (Mitochondrial dynamics protein of 51 kDa) (Mitochondrial elongation factor 1) (Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like) (SMCR7-like protein), MIEF1, MID51 SMCR7L |
UniProt Protein Function: | SMCR7L: Mitochondrial outer membrane protein which regulates mitochondrial morphology. Mitochondrial morphology is controlled by two opposites processes: fusion and fission. Seems to have a key role in inhibiting DNM1L-induced mitochondrial fission. Belongs to the SMCR7 family. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 22q13 Cellular Component: mitochondrial outer membrane; mitochondrion; integral to membrane; peroxisome Molecular Function:identical protein binding; protein binding; GDP binding; ADP binding Biological Process: mitochondrial fission; mitochondrial fusion |
UniProt Code: | Q9NQG6 |
NCBI GenInfo Identifier: | 74752902 |
NCBI Gene ID: | 54471 |
NCBI Accession: | Q9NQG6.1 |
UniProt Secondary Accession: | Q9NQG6,Q7L890, Q9BUI3, |
UniProt Related Accession: | Q9NQG6 |
Molecular Weight: | Calculated MW: 8kDa/15kDa/51kDaObserved MW: 51kDa |
NCBI Full Name: | Mitochondrial dynamics protein MID51 |
NCBI Synonym Full Names: | mitochondrial elongation factor 1 |
NCBI Official Symbol: | MIEF1 |
NCBI Official Synonym Symbols: | MID51; SMCR7L; HSU79252; dJ1104E15.3 |
NCBI Protein Information: | mitochondrial dynamics protein MID51; SMCR7-like protein; mitochondrial dynamic protein MID51; mitochondrial dynamic protein of 51 kDa; mitochondrial dynamics protein of 51 kDa; Smith-Magenis syndrome chromosome region, candidate 7-like; smith-Magenis syndrome chromosomal region candidate gene 7 protein-like |
UniProt Protein Name: | Mitochondrial dynamics protein MID51 |
UniProt Synonym Protein Names: | Mitochondrial dynamics protein of 51 kDa; Mitochondrial elongation factor 1; Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like; SMCR7-like protein |
Protein Family: | Mitochondrial dynamics protein |
UniProt Gene Name: | MIEF1 |
UniProt Entry Name: | MID51_HUMAN |