MGAT5 Antibody (PACO60957)
- SKU:
- PACO60957
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | MGAT5 Antibody (PACO60957) |
抗体コード: | PACO60957 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IF |
推奨される希釈: | ELISA:1:2000-1:10000, IF:1:200-1:500 |
反応性: | Human |
免疫原: | Recombinant Human Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A protein (107-217AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunofluorescence staining of HepG2 cells with PACO60957 at 1:200, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
バックグラウンド: | Catalyzes the addition of N-acetylglucosamine in β 1-6 linkage to the alpha-linked mannose of biantennary N-linked oligosaccharides. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. |
シノニム: | Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (EC 2.4.1.155) (Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase) (GlcNAc-T V) (GNT-V) (Mannoside acetylglucosaminyltransferase 5) (N-acetylglucosaminyl-transferase V), MGAT5, GGNT5 |
UniProt Protein Function: | Catalyzes the addition of N-acetylglucosamine in beta 1-6 linkage to the alpha-linked mannose of biantennary N-linked oligosaccharides. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. |
NCBI Summary: | The protein encoded by this gene belongs to the glycosyltransferase family. It catalyzes the addition of beta-1,6-N-acetylglucosamine to the alpha-linked mannose of biantennary N-linked oligosaccharides present on the newly synthesized glycoproteins. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. Alterations of the oligosaccharides on cell surface glycoproteins cause significant changes in the adhesive or migratory behavior of a cell. Increase in the activity of this enzyme has been correlated with the progression of invasive malignancies. [provided by RefSeq, Oct 2011] |
UniProt Code: | Q09328 |
NCBI GenInfo Identifier: | 4505167 |
NCBI Gene ID: | 4249 |
NCBI Accession: | NP_002401.1 |
UniProt Secondary Accession: | Q09328,D3DP70, |
UniProt Related Accession: | Q09328 |
Molecular Weight: | 84,543 Da |
NCBI Full Name: | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A |
NCBI Synonym Full Names: | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase |
NCBI Official Symbol: | MGAT5 |
NCBI Official Synonym Symbols: | GNT-V; GNT-VA |
NCBI Protein Information: | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A |
UniProt Protein Name: | Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A |
UniProt Synonym Protein Names: | Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase; GlcNAc-T V; GNT-V; Mannoside acetylglucosaminyltransferase 5; N-acetylglucosaminyl-transferase V |
Protein Family: | Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase |
UniProt Gene Name: | MGAT5 |
Antibodies |
Anti-MGAT5 Antibody (CAB10567) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-HRP-conjugated Beta Actin Antibody (CABC028) |