MFN1 Antibody (PACO14698)
- SKU:
- PACO14698
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | MFN1 Antibody (PACO14698) |
抗体コード: | PACO14698 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
反応性: | Human, Mouse, Rat |
免疫原: | Fusion protein of human MFN1 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO14698(MFN1 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting. Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks |
シノニム: | mitofusin 1 |
UniProt Protein Function: | MFN1: Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks. Belongs to the mitofusin family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; EC 3.6.5.-; Mitochondrial; Hydrolase; Membrane protein, integral Chromosomal Location of Human Ortholog: 3q26.33 Cellular Component: mitochondrial outer membrane; mitochondrion Molecular Function:protein binding Biological Process: macroautophagy; mitochondrial fusion |
NCBI Summary: | The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q8IWA4 |
NCBI GenInfo Identifier: | 150421594 |
NCBI Gene ID: | 55669 |
NCBI Accession: | Q8IWA4.2 |
UniProt Secondary Accession: | Q8IWA4,O15323, O60639, Q9BZB5, Q9NWQ2, B2RAR1, D3DNR6 |
UniProt Related Accession: | Q8IWA4 |
Molecular Weight: | 71,401 Da |
NCBI Full Name: | Mitofusin-1 |
NCBI Synonym Full Names: | mitofusin 1 |
NCBI Official Symbol: | MFN1 |
NCBI Official Synonym Symbols: | hfzo1; hfzo2 |
NCBI Protein Information: | mitofusin-1 |
UniProt Protein Name: | Mitofusin-1 |
UniProt Synonym Protein Names: | Fzo homolog; Transmembrane GTPase MFN1 |
Protein Family: | Mitofusin |
UniProt Gene Name: | MFN1 |
UniProt Entry Name: | MFN1_HUMAN |
Antibodies | ELISA Kits |
Anti-Mitofusin-1 Antibody (CAB9880) | Human MFN1 (Mitofusin 1) ELISA Kit (HUFI07635) |
MFN1 Antibody (PACO10473) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-HRP-conjugated Beta Actin Antibody (CABC028) |