MEX3B Antibody (PACO60148)
- SKU:
- PACO60148
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | MEX3B Antibody (PACO60148) |
抗体コード: | PACO60148 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:200-1:500, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human RNA-binding protein MEX3B protein (253-375AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | IHC image of PACO60148 diluted at 1:300 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
![]() | Immunofluorescence staining of SH-SY5Y cells with PACO60148 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
![]() | IHC image of PACO60148 diluted at 1:300 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
バックグラウンド: | RNA-binding protein. May be involved in post-transcriptional regulatory mechanisms. |
シノニム: | RNA-binding protein MEX3B (RING finger and KH domain-containing protein 3) (RING finger protein 195), MEX3B, KIAA2009 RKHD3 RNF195 |
UniProt Protein Function: | RKHD3: RNA-binding protein. May be involved in post- transcriptional regulatory mechanisms. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:RNA-binding; Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 15q25.2 Molecular Function:calcium ion binding Biological Process: protein amino acid autophosphorylation; protein amino acid phosphorylation |
NCBI Summary: | This gene encodes an RNA-binding phosphoprotein that is part of the MEX3 (muscle excess 3) family of translational regulators. The encoded protein contains N-terminal nuclear export and nuclear localization signals and is exported from the cytoplasm to the nucleus. The protein binds to RNA via two KH domains and also colocalizes with MEX3A, Dcp1A decapping factor and Argonaute proteins within P (processing) bodies. [provided by RefSeq, Oct 2012] |
UniProt Code: | Q6ZN04 |
NCBI GenInfo Identifier: | 74762391 |
NCBI Gene ID: | 84206 |
NCBI Accession: | Q6ZN04.1 |
UniProt Secondary Accession: | Q6ZN04,Q4G0W1, Q8IVG2, Q9H0J0, |
UniProt Related Accession: | Q6ZN04 |
Molecular Weight: | 16,780 Da |
NCBI Full Name: | RNA-binding protein MEX3B |
NCBI Synonym Full Names: | mex-3 RNA binding family member B |
NCBI Official Symbol: | MEX3B |
NCBI Official Synonym Symbols: | RKHD3; MEX-3B; RNF195 |
NCBI Protein Information: | RNA-binding protein MEX3B |
UniProt Protein Name: | RNA-binding protein MEX3B |
UniProt Synonym Protein Names: | RING finger and KH domain-containing protein 3; RING finger protein 195 |
Protein Family: | RNA-binding protein |
UniProt Gene Name: | MEX3B |
UniProt Entry Name: | MEX3B_HUMAN |
Antibodies |
Anti-MEX3B Antibody (CAB16763) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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