Metrnl Antibody, Biotin conjugated (PACO52705)
- SKU:
- PACO52705
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | Metrnl Antibody, Biotin conjugated (PACO52705) |
抗体コード: | PACO52705 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Mouse |
免疫原: | Recombinant Mouse Meteorin-like protein (46-311AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Hormone induced following exercise or cold exposure that promotes energy expenditure. Induced either in the skeletal muscle after exercise or in adipose tissue following cold exposure and is present in the circulation. Able to stimulate energy expenditure associated with the browning of the white fat depots and improves glucose tolerance. Does not promote an increase in a thermogenic gene program via direct action on adipocytes, but acts by stimulating several immune cell subtypes to enter the adipose tissue and activate their prothermogenic actions. Stimulates an eosinophil-dependent increase in IL4 expression and promotes alternative activation of adipose tissue macrophages, which are required for the increased expression of the thermogenic and anti-inflammatory gene programs in fat. Required for some cold-induced thermogenic responses, suggesting a role in metabolic adaptations to cold temperatures. |
シノニム: | Meteorin-like protein (Subfatin), Metrnl |
UniProt Protein Function: | METRNL: Belongs to the meteorin family. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Cellular Component: extracellular space; extracellular region Molecular Function:hormone activity Biological Process: fat cell differentiation; response to muscle activity; negative regulation of inflammatory response; brown fat cell differentiation; response to cold |
UniProt Code: | Q8VE43 |
NCBI GenInfo Identifier: | 21450153 |
NCBI Gene ID: | 210029 |
NCBI Accession: | NP_659046.1 |
UniProt Secondary Accession: | Q8VE43,Q8R1J2, |
UniProt Related Accession: | Q8VE43 |
Molecular Weight: | 34,530 Da |
NCBI Full Name: | meteorin-like protein |
NCBI Synonym Full Names: | meteorin, glial cell differentiation regulator-like |
NCBI Official Symbol: | Metrnl |
NCBI Official Synonym Symbols: | BC019776; 9430048M07Rik |
NCBI Protein Information: | meteorin-like protein; cometin |
UniProt Protein Name: | Meteorin-like protein |
UniProt Synonym Protein Names: | Subfatin |
Protein Family: | Meteorin-like protein |
UniProt Gene Name: | Metrnl |
UniProt Entry Name: | METRL_MOUSE |