MED30 Antibody, FITC conjugated (PACO38160)
- SKU:
- PACO38160
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | MED30 Antibody, FITC conjugated (PACO38160) |
抗体コード: | PACO38160 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Mediator of RNA polymerase II transcription subunit 30 protein (67-165AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
シノニム: | Mediator of RNA polymerase II transcription subunit 30 (Mediator complex subunit 30) (TRAP/Mediator complex component TRAP25) (Thyroid hormone receptor-associated protein 6) (Thyroid hormone receptor-associated protein complex 25 kDa component) (Trap25), MED30, THRAP6 TRAP25 |
UniProt Protein Function: | MED30: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Belongs to the Mediator complex subunit 30 family. |
UniProt Protein Details: | Protein type:Nuclear receptor co-regulator Chromosomal Location of Human Ortholog: 8q24.11 Cellular Component: nucleoplasm; nucleus; Srb-mediator complex Molecular Function:protein binding; receptor activity; thyroid hormone receptor binding; transcription cofactor activity Biological Process: androgen receptor signaling pathway; positive regulation of transcription, DNA-dependent; steroid hormone receptor signaling pathway; transcription initiation from RNA polymerase II promoter |
NCBI Summary: | The multiprotein TRAP/Mediator complex facilitates gene expression through a wide variety of transcriptional activators. MED30 is a component of this complex that appears to be metazoan specific (Baek et al., 2002 [PubMed 11909976]).[supplied by OMIM, Nov 2010] |
UniProt Code: | Q96HR3 |
NCBI GenInfo Identifier: | 74731968 |
NCBI Gene ID: | 90390 |
NCBI Accession: | Q96HR3.1 |
UniProt Secondary Accession: | Q96HR3,C6GKU9, |
UniProt Related Accession: | Q96HR3 |
Molecular Weight: | 16,279 Da |
NCBI Full Name: | Mediator of RNA polymerase II transcription subunit 30 |
NCBI Synonym Full Names: | mediator complex subunit 30 |
NCBI Official Symbol: | MED30 |
NCBI Official Synonym Symbols: | MED30S; THRAP6; TRAP25 |
NCBI Protein Information: | mediator of RNA polymerase II transcription subunit 30 |
UniProt Protein Name: | Mediator of RNA polymerase II transcription subunit 30 |
UniProt Synonym Protein Names: | Mediator complex subunit 30; TRAP/Mediator complex component TRAP25; Thyroid hormone receptor-associated protein 6; Thyroid hormone receptor-associated protein complex 25 kDa component; Trap25 |
Protein Family: | Mediator of RNA polymerase II transcription |
UniProt Gene Name: | MED30 |
UniProt Entry Name: | MED30_HUMAN |