MEAF6 Antibody (PACO59413)
- SKU:
- PACO59413
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | MEAF6 Antibody (PACO59413) |
抗体コード: | PACO59413 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:200-1:500 |
反応性: | Human |
免疫原: | Recombinant Human Chromatin modification-related protein MEAF6 protein (113-174AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | IHC image of PACO59413 diluted at 1:200 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
バックグラウンド: | Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. |
シノニム: | Chromatin modification-related protein MEAF6 (MYST/Esa1-associated factor 6) (Esa1-associated factor 6 homolog) (Protein EAF6 homolog) (hEAF6) (Sarcoma antigen NY-SAR-91), MEAF6, C1orf149 CENP-28 EAF6 |
UniProt Protein Function: | MEAF6: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Belongs to the EAF6 family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Nucleolus; Unknown function Chromosomal Location of Human Ortholog: 1p35.3-p33 Cellular Component: centrosome; cytoplasm; NuA4 histone acetyltransferase complex; nucleolus; nucleoplasm Molecular Function:protein binding |
NCBI Summary: | This gene encodes a nuclear protein involved in transcriptional activation. The encoded protein may form a component of several different histone acetyltransferase complexes. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] |
UniProt Code: | Q9HAF1 |
NCBI GenInfo Identifier: | 74752760 |
NCBI Gene ID: | 64769 |
NCBI Accession: | Q9HAF1.1 |
UniProt Secondary Accession: | Q9HAF1,Q4F967, Q7Z311, Q86WE3, B1AK64, |
UniProt Related Accession: | Q9HAF1 |
Molecular Weight: | 21,709 Da |
NCBI Full Name: | Chromatin modification-related protein MEAF6 |
NCBI Synonym Full Names: | MYST/Esa1 associated factor 6 |
NCBI Official Symbol: | MEAF6 |
NCBI Official Synonym Symbols: | EAF6; CENP-28; C1orf149; NY-SAR-91 |
NCBI Protein Information: | chromatin modification-related protein MEAF6 |
UniProt Protein Name: | Chromatin modification-related protein MEAF6 |
UniProt Synonym Protein Names: | Esa1-associated factor 6 homolog; Protein EAF6 homolog; hEAF6; Sarcoma antigen NY-SAR-91 |
Protein Family: | Chromatin modification-related protein |
UniProt Gene Name: | MEAF6 |
UniProt Entry Name: | EAF6_HUMAN |
Antibodies |
Anti-MEAF6 Antibody (CAB14629) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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