MCUB Antibody (PACO41186)
- SKU:
- PACO41186
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| 抗体名: | MCUB Antibody (PACO41186) |
| 抗体コード: | PACO41186 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, IHC, IF |
| 推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| 反応性: | Human |
| 免疫原: | Recombinant Human Calcium uniporter regulatory subunit MCUb, mitochondrial protein (89-219AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO41186 at dilution of 1:100. |
 | Immunofluorescent analysis of A549 cells using PACO41186 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| バックグラウンド: | Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways. |
| シノニム: | Calcium uniporter regulatory subunit MCUb, mitochondrial (MCUb) (Coiled-coil domain-containing protein 109B), MCUB, CCDC109B |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9NWR8 |
| NCBI GenInfo Identifier: | 194018570 |
| NCBI Gene ID: | 55013 |
| NCBI Accession: | NP_060388.2 |
| UniProt Secondary Accession: | Q9NWR8,Q6IAC1, A8K4Y3 |
| UniProt Related Accession: | Q9NWR8 |
| Molecular Weight: | 39,082 Da |
| NCBI Full Name: | mitochondrial calcium uniporter regulatory subunit MCUb |
| NCBI Synonym Full Names: | coiled-coil domain containing 109B |
| NCBI Official Symbol: | CCDC109B |
| NCBI Official Synonym Symbols: | EMRE; MCUb |
| NCBI Protein Information: | mitochondrial calcium uniporter regulatory subunit MCUb; essential MCU regulator; coiled-coil domain-containing protein 109B |
| UniProt Protein Name: | Mitochondrial calcium uniporter regulatory subunit MCUb |
| UniProt Synonym Protein Names: | Coiled-coil domain-containing protein 109B; Essential MCU regulator; EMRE |
| Protein Family: | Calcium uniporter regulatory |
| UniProt Gene Name: | CCDC109B |
| UniProt Entry Name: | MCUB_HUMAN |