MARVELD1 Antibody (PACO19991)
- SKU:
- PACO19991
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | MARVELD1 Antibody (PACO19991) |
抗体コード: | PACO19991 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:50-1:200 |
反応性: | Human, Mouse |
免疫原: | Synthetic peptide of human MARVELD1 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO19991(MARVELD1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Mouse heart tissue, Primary antibody: PACO19991(MARVELD1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes. | |
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO19991(MARVELD1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | MARVELD1 (MARVEL domain containing 1), also known as GB14, MARVD1 or MRVLDC1, is a 173 amino acid, protein that is widely expressed and contains one MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain. The MARVEL domain, which is common in Occludin proteins, is a 130 amino acid, motif that contains four transmembrane helices, both of which have cytoplasmic N- and C-terminal regions. Localizing to the nucleus, MARVELD1 is downregulated in primary multiple tumors of liver, bladder, ovary, vulva, breast, testis, uterus, kidney and testis. The gene encoding MARVELD1 maps to human chromosome 10, which makes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome and Cowden syndrome. |
シノニム: | MARVEL domain containing 1 |
UniProt Protein Function: | MARVELD1: Microtubule-associated protein that exhibits cell cycle- dependent localization and can inhibit cell proliferation and migration. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 10q24.2 Cellular Component: cytoskeleton; cytoplasm; plasma membrane; integral to membrane; nucleus Biological Process: cell cycle |
UniProt Code: | Q9BSK0 |
NCBI GenInfo Identifier: | 13899344 |
NCBI Gene ID: | 83742 |
NCBI Accession: | NP_113672.1 |
UniProt Related Accession: | Q9BSK0 |
Molecular Weight: | 18,914 Da |
NCBI Full Name: | MARVEL domain-containing protein 1 |
NCBI Synonym Full Names: | MARVEL domain containing 1 |
NCBI Official Symbol: | MARVELD1 |
NCBI Official Synonym Symbols: | GB14; MARVD1; MRVLDC1; bA548K23.8 |
NCBI Protein Information: | MARVEL domain-containing protein 1 |
UniProt Protein Name: | MARVEL domain-containing protein 1 |
Protein Family: | MARVEL domain-containing protein |
UniProt Gene Name: | MARVELD1 |
UniProt Entry Name: | MALD1_HUMAN |
Antibodies |
Anti-MARVELD1 Antibody (CAB17787) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |