MARCKSL1 Antibody (PACO10392)
- SKU:
- PACO10392
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | MARCKSL1 Antibody (PACO10392) |
抗体コード: | PACO10392 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | |
反応性: | Human, Mouse |
免疫原: | Human Marcksl1 |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | MARCKS-like 1;Marcksl1;AL022768;AW215397;AW536807;D4Bc1;F52;MacMARCKS;Macs-2;Macs-3;Macs2;Macs3;Mlp;Mrp ; |
UniProt Protein Function: | MLP: Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation. When unphosphorylated, induces cell migration. When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration. May also affect cancer cell migration. May be involved in coupling the protein kinase C and calmodulin signal transduction systems. Belongs to the MARCKS family. |
UniProt Protein Details: | Protein type:Cell cycle regulation Chromosomal Location of Human Ortholog: 1p35.1 Cellular Component: cytoplasm; plasma membrane Molecular Function:calmodulin binding; actin binding Biological Process: positive regulation of cell proliferation |
NCBI Summary: | This gene encodes a member of the myristoylated alanine-rich C-kinase substrate (MARCKS) family. Members of this family play a role in cytoskeletal regulation, protein kinase C signaling and calmodulin signaling. The encoded protein affects the formation of adherens junction. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are located on the long arm of chromosomes 6 and 10. [provided by RefSeq, Jun 2012] |
UniProt Code: | P49006 |
NCBI GenInfo Identifier: | 1346576 |
NCBI Gene ID: | 65108 |
NCBI Accession: | P49006.2 |
UniProt Related Accession: | P49006 |
Molecular Weight: | |
NCBI Full Name: | MARCKS-related protein |
NCBI Synonym Full Names: | MARCKS like 1 |
NCBI Official Symbol: | MARCKSL1 |
NCBI Official Synonym Symbols: | F52; MLP; MRP; MLP1; MACMARCKS |
NCBI Protein Information: | MARCKS-related protein |
UniProt Protein Name: | MARCKS-related protein |
UniProt Synonym Protein Names: | MARCKS-like protein 1; Macrophage myristoylated alanine-rich C kinase substrate; Mac-MARCKS; MacMARCKS |
Protein Family: | MIP-related peptides |
UniProt Gene Name: | MARCKSL1 |
UniProt Entry Name: | MRP_HUMAN |