MAPK6 Antibody, FITC conjugated (PACO51692)
- SKU:
- PACO51692
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | MAPK6 Antibody, FITC conjugated (PACO51692) |
抗体コード: | PACO51692 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Mitogen-activated protein kinase 6 protein (383-712AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle (By similarity). |
シノニム: | Mitogen-activated protein kinase 6 (MAP kinase 6) (MAPK 6) (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97-MAPK), MAPK6, ERK3 PRKM6 |
UniProt Protein Function: | ERK3: a protein kinase of the MAPK family. Plays a critical role in the regulation of cell growth and differentiation. Localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. |
UniProt Protein Details: | Protein type:Protein kinase, Ser/Thr (non-receptor); Protein kinase, CMGC; Kinase, protein; EC 2.7.11.24; CMGC group; MAPK family; MAPK/ERK subfamily; ERK subfamily Chromosomal Location of Human Ortholog: 15q21 Cellular Component: cytoplasm; cytosol; nucleoplasm; nucleus Molecular Function:MAP kinase activity; protein binding; protein serine/threonine kinase activity Biological Process: protein amino acid phosphorylation; signal transduction |
NCBI Summary: | The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q16659 |
NCBI GenInfo Identifier: | 2499596 |
NCBI Gene ID: | 5597 |
NCBI Accession: | Q16659.1 |
UniProt Secondary Accession: | Q16659,Q68DH4, Q8IYN8, B2R945, B5BU65, |
UniProt Related Accession: | Q16659 |
Molecular Weight: | 82,681 Da |
NCBI Full Name: | Mitogen-activated protein kinase 6 |
NCBI Synonym Full Names: | mitogen-activated protein kinase 6 |
NCBI Official Symbol: | MAPK6 |
NCBI Official Synonym Symbols: | ERK3; PRKM6; p97MAPK; HsT17250 |
NCBI Protein Information: | mitogen-activated protein kinase 6 |
UniProt Protein Name: | Mitogen-activated protein kinase 6 |
UniProt Synonym Protein Names: | Extracellular signal-regulated kinase 3; ERK-3; MAP kinase isoform p97; p97-MAPK |
UniProt Gene Name: | MAPK6 |
UniProt Entry Name: | MK06_HUMAN |