MAOB Antibody (PACO28130)
- SKU:
- PACO28130
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | MAOB Antibody (PACO28130) |
抗体コード: | PACO28130 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:500 |
反応性: | Human, Mouse |
免疫原: | Recombinant Human Amine oxidase [flavin-containing] B protein (2-489AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot All lanes: MAOB antibody at 9µg/ml Lane 1: Mouse liver tissue Lane 2: HepG2 whole cell lysate Lane 3: A549 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 59, 47 kDa Observed band size: 59, 27 kDa . |
![]() | IHC image of PACO28130 diluted at 1:300 and staining in paraffin-embedded human lymph node tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
![]() | Immunohistochemistry of paraffin-embedded mouse liver tissue using PACO28130 at dilution of 1:50. |
バックグラウンド: | Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine. |
シノニム: | Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B), MAOB |
UniProt Protein Function: | MAOB: Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine. Belongs to the flavin monoamine oxidase family. |
UniProt Protein Details: | Protein type:Mitochondrial; Amino Acid Metabolism - arginine and proline; EC 1.4.3.4; Amino Acid Metabolism - tyrosine; Amino Acid Metabolism - glycine, serine and threonine; Amino Acid Metabolism - histidine; Membrane protein, integral; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Oxidoreductase; Amino Acid Metabolism - phenylalanine; Amino Acid Metabolism - tryptophan Chromosomal Location of Human Ortholog: Xp11.23 Cellular Component: mitochondrial envelope; mitochondrial outer membrane; mitochondrion; mitochondrial inner membrane; integral to membrane Molecular Function:amine oxidase activity; protein homodimerization activity; electron carrier activity; FAD binding Biological Process: response to drug; negative regulation of serotonin secretion; positive regulation of dopamine metabolic process; response to selenium ion; response to ethanol; substantia nigra development; dopamine catabolic process; response to toxin; xenobiotic metabolic process; response to lipopolysaccharide; hydrogen peroxide biosynthetic process; response to corticosterone stimulus; response to aluminum ion |
NCBI Summary: | The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. [provided by RefSeq, Jul 2008] |
UniProt Code: | P27338 |
NCBI GenInfo Identifier: | 113980 |
NCBI Gene ID: | 4129 |
NCBI Accession: | P27338.3 |
UniProt Secondary Accession: | P27338,Q7Z6S2, B2R6R3, B7Z5H3, D3DWC3, |
UniProt Related Accession: | P27338 |
Molecular Weight: | 520 |
NCBI Full Name: | Amine oxidase |
NCBI Synonym Full Names: | monoamine oxidase B |
NCBI Official Symbol: | MAOB |
NCBI Protein Information: | amine oxidase [flavin-containing] B; amine oxidase [flavin-containing] B; MAO-B; MAO, brain; MAO, platelet; tyramine oxidase; adrenalin oxidase; monoamine oxidase type B |
UniProt Protein Name: | Amine oxidase [flavin-containing] B |
UniProt Synonym Protein Names: | Monoamine oxidase type B; MAO-B |
Protein Family: | Amine oxidase |
UniProt Gene Name: | MAOB |
UniProt Entry Name: | AOFB_HUMAN |
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