LYZ Antibody (PACO31556)
- SKU:
- PACO31556
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | LYZ Antibody (PACO31556) |
抗体コード: | PACO31556 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Lysozyme C protein (19-148AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO31556 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human gastric cancer using PACO31556 at dilution of 1:100. |
バックグラウンド: | Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. |
シノニム: | Lysozyme C (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase C), LYZ, LZM |
UniProt Protein Function: | LYZ: Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte- macrophage system and enhance the activity of immunoagents. Defects in LYZ are a cause of amyloidosis type 8 (AMYL8); also known as systemic non-neuropathic amyloidosis or Ostertag-type amyloidosis. AMYL8 is a hereditary generalized amyloidosis due to deposition of apolipoprotein A1, fibrinogen and lysozyme amyloids. Viscera are particularly affected. There is no involvement of the nervous system. Clinical features include renal amyloidosis resulting in nephrotic syndrome, arterial hypertension, hepatosplenomegaly, cholestasis, petechial skin rash. Belongs to the glycosyl hydrolase 22 family. |
UniProt Protein Details: | Protein type:EC 3.2.1.17; Endoplasmic reticulum; Secreted, signal peptide; Vesicle; Secreted; Hydrolase Chromosomal Location of Human Ortholog: 12q15 Cellular Component: extracellular space; extracellular region Molecular Function:identical protein binding; lysozyme activity Biological Process: retinal homeostasis; metabolic process; cytolysis; defense response to bacterium; inflammatory response Disease: Amyloidosis, Familial Visceral |
NCBI Summary: | This gene encodes human lysozyme, whose natural substrate is the bacterial cell wall peptidoglycan (cleaving the beta[1-4]glycosidic linkages between N-acetylmuramic acid and N-acetylglucosamine). Lysozyme is one of the antimicrobial agents found in human milk, and is also present in spleen, lung, kidney, white blood cells, plasma, saliva, and tears. The protein has antibacterial activity against a number of bacterial species. Missense mutations in this gene have been identified in heritable renal amyloidosis. [provided by RefSeq, Oct 2014] |
UniProt Code: | P61626 |
NCBI GenInfo Identifier: | 48428995 |
NCBI Gene ID: | 4069 |
NCBI Accession: | P61626.1 |
UniProt Related Accession: | P61626 |
Molecular Weight: | ~ 17kDa |
NCBI Full Name: | Lysozyme C |
NCBI Synonym Full Names: | lysozyme |
NCBI Official Symbol: | LYZ |
NCBI Official Synonym Symbols: | LZM; LYZF1 |
NCBI Protein Information: | lysozyme C |
UniProt Protein Name: | Lysozyme C |
UniProt Synonym Protein Names: | 1,4-beta-N-acetylmuramidase C |
UniProt Gene Name: | LYZ |
UniProt Entry Name: | LYSC_HUMAN |
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