LSM1 Antibody, HRP conjugated (PACO28034)
- SKU:
- PACO28034
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | LSM1 Antibody, HRP conjugated (PACO28034) |
抗体コード: | PACO28034 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human U6 snRNA-associated Sm-like protein LSm1 protein (1-133AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Plays a role in replication-dependent histone mRNA degradation. Binds specifically to the 3'-terminal U-tract of U6 snRNA. |
シノニム: | U6 snRNA-associated Sm-like protein LSm1 (Cancer-associated Sm-like) (Small nuclear ribonuclear CaSm), LSM1, CASM |
UniProt Protein Function: | LSM1: Plays a role in replication-dependent histone mRNA degradation. Binds specifically to the 3'-terminal U-tract of U6 snRNA. Belongs to the snRNP Sm proteins family. |
UniProt Protein Details: | Protein type:RNA-binding Chromosomal Location of Human Ortholog: 8p11.23 Cellular Component: cytoplasm; cytosol; nucleus Molecular Function:protein binding; RNA binding; RNA cap binding Biological Process: deadenylation-dependent decapping; RNA splicing; RNA splicing, via transesterification reactions |
NCBI Summary: | This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Nov 2011] |
UniProt Code: | O15116 |
NCBI GenInfo Identifier: | 20177943 |
NCBI Gene ID: | 27257 |
NCBI Accession: | O15116.1 |
UniProt Secondary Accession: | O15116,B2R5E6, |
UniProt Related Accession: | O15116 |
Molecular Weight: | 15kDa |
NCBI Full Name: | U6 snRNA-associated Sm-like protein LSm1 |
NCBI Synonym Full Names: | LSM1 homolog, mRNA degradation associated |
NCBI Official Symbol: | LSM1 |
NCBI Official Synonym Symbols: | CASM; YJL124C |
NCBI Protein Information: | U6 snRNA-associated Sm-like protein LSm1 |
UniProt Protein Name: | U6 snRNA-associated Sm-like protein LSm1 |
UniProt Synonym Protein Names: | Cancer-associated Sm-like; Small nuclear ribonuclear CaSm |
Protein Family: | Sm-like protein |
UniProt Gene Name: | LSM1 |