LSAMP Antibody, Biotin conjugated (PACO57851)
- SKU:
- PACO57851
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | LSAMP Antibody, Biotin conjugated (PACO57851) |
抗体コード: | PACO57851 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Limbic system-associated membrane protein (168-287AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Mediates selective neuronal growth and axon targeting. Contributes to the guidance of developing axons and remodeling of mature circuits in the limbic system. Essential for normal growth of the hyppocampal mossy fiber projection (By similarity). |
シノニム: | Limbic system-associated membrane protein (LSAMP) (IgLON family member 3), LSAMP, IGLON3 LAMP |
UniProt Protein Function: | APCS: Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin. SAP is a precursor of amyloid component P which is found in basement membrane and associated with amyloid deposits. Belongs to the pentaxin family. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted; Chaperone Chromosomal Location of Human Ortholog: 1q21-q23 Cellular Component: extracellular matrix; extracellular space; protein complex; extracellular region; nucleus Molecular Function:complement component C1q binding; unfolded protein binding; virion binding; calcium ion binding; carbohydrate binding Biological Process: protein folding; negative regulation of virion penetration into host cell; acute-phase response; negative regulation of acute inflammatory response; innate immune response; chaperone-mediated protein complex assembly; negative regulation of monocyte differentiation; negative regulation of viral reproduction |
NCBI Summary: | The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. [provided by RefSeq, Sep 2008] |
UniProt Code: | Q13449 |
NCBI GenInfo Identifier: | 4502133 |
NCBI Gene ID: | 325 |
NCBI Accession: | NP_001630.1 |
UniProt Secondary Accession: | Q13449,Q13449, |
UniProt Related Accession: | P02743 |
Molecular Weight: | 25,387 Da |
NCBI Full Name: | serum amyloid P-component |
NCBI Synonym Full Names: | amyloid P component, serum |
NCBI Official Symbol: | APCS |
NCBI Official Synonym Symbols: | SAP; PTX2 |
NCBI Protein Information: | serum amyloid P-component; pentaxin-related; 9.5S alpha-1-glycoprotein |
UniProt Protein Name: | Serum amyloid P-component |
UniProt Synonym Protein Names: | 9.5S alpha-1-glycoprotein |
UniProt Gene Name: | APCS |
UniProt Entry Name: | SAMP_HUMAN |