LPAR4 Antibody (PACO28005)
- SKU:
- PACO28005
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | LPAR4 Antibody (PACO28005) |
抗体コード: | PACO28005 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:200-1:500, IF:1:50-1:200 |
反応性: | Human, Mouse |
免疫原: | Recombinant Human Lysophosphatidic acid, receptor 4 protein (1-43AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western blot All lanes: LPAR4 antibody at 4µg/ml + Mouse kidney tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 42 kDa Observed band size: 42 kDa . | |
IHC image of PACO28005 diluted at 1:200 and staining in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. | |
Immunofluorescent analysis of HepG2 cells using PACO28005 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
バックグラウンド: | Receptor for lysophosphatidic acid, (LPA), a mediator of diverse cellular activities. Transduces a signal by increasing the intracellular calcium ions and by stimulating adenylyl cyclase activity. The rank order of potency for agonists of this receptor is 1-oleoyl- > 1-stearoyl- > 1-palmitoyl- > 1-myristoyl- > 1-alkyl- > 1-alkenyl-LPA. |
シノニム: | Lysophosphatidic acid, receptor 4 (LPA receptor 4) (LPA-4) (G-protein coupled receptor 23) (P2Y purinoceptor 9) (P2Y9) (P2Y5-like receptor) (Purinergic receptor 9), LPAR4, GPR23 LPA4 P2RY9 |
UniProt Protein Function: | LPAR4: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Transduces a signal by increasing the intracellular calcium ions and by stimulating adenylyl cyclase activity. The rank order of potency for agonists of this receptor is 1-oleoyl- > 1-stearoyl- > 1-palmitoyl- > 1-myristoyl- > 1- alkyl- > 1-alkenyl-LPA. Belongs to the G-protein coupled receptor 1 family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: Xq21.1 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:G-protein coupled receptor activity; lipid binding Biological Process: G-protein coupled receptor protein signaling pathway |
NCBI Summary: | This gene encodes a member of the lysophosphatidic acid receptor family. It may also be related to the P2Y receptors, a family of receptors that bind purine and pyrimidine nucleotides and are coupled to G proteins. The encoded protein may play a role in monocytic differentiation. [provided by RefSeq, Feb 2009] |
UniProt Code: | Q99677 |
NCBI GenInfo Identifier: | 2495042 |
NCBI Gene ID: | 2846 |
NCBI Accession: | Q99677.1 |
UniProt Secondary Accession: | Q99677,O15132, Q502U9, Q6NSP5, B2RAC7, |
UniProt Related Accession: | Q99677 |
Molecular Weight: | 41,895 Da |
NCBI Full Name: | Lysophosphatidic acid receptor 4 |
NCBI Synonym Full Names: | lysophosphatidic acid receptor 4 |
NCBI Official Symbol: | LPAR4 |
NCBI Official Synonym Symbols: | LPA4; P2Y9; GPR23; P2RY9; P2Y5-LIKE |
NCBI Protein Information: | lysophosphatidic acid receptor 4; G protein-coupled receptor 23; G-protein coupled receptor 23; LPA receptor 4; LPA-4; P2Y purinoceptor 9; P2Y5-like receptor; purinergic receptor 9 |
UniProt Protein Name: | Lysophosphatidic acid receptor 4 |
UniProt Synonym Protein Names: | G-protein coupled receptor 23; P2Y purinoceptor 9; P2Y9; P2Y5-like receptor; Purinergic receptor 9 |
Protein Family: | Lysophosphatidic acid receptor |
UniProt Gene Name: | LPAR4 |
UniProt Entry Name: | LPAR4_HUMAN |
Antibodies | ELISA Kits |
Anti-LPAR4 Antibody (CAB3060) | Human LPAR4 / Lysophosphatidic acid receptor 4 ELISA Kit |
Human Lysophosphatidic acid receptor 4 (LPAR4) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |