LPAR2 Antibody, Biotin conjugated (PACO63346)
- SKU:
- PACO63346
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | LPAR2 Antibody, Biotin conjugated (PACO63346) |
抗体コード: | PACO63346 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Peptide sequence from Human Lysophosphatidic acid, receptor 2 protein (8-27AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Receptor for lysophosphatidic acid, (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-β (PLC-beta) signaling pathway. Stimulates phospholipase C (PLC) activity in a manner that is independent of RALA activation. |
シノニム: | Lysophosphatidic acid, receptor 2 (LPA receptor 2) (LPA-2) (Lysophosphatidic acid, receptor Edg-4), LPAR2, EDG4 LPA2 |
UniProt Protein Function: | EDG4: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway. Stimulates phospholipase C (PLC) activity in a manner that is independent of RALA activation. Belongs to the G-protein coupled receptor 1 family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR Chromosomal Location of Human Ortholog: 19p12 Cellular Component: cell surface; endocytic vesicle; integral to plasma membrane; plasma membrane Molecular Function:G-protein coupled receptor activity; lipid binding; protein binding Biological Process: elevation of cytosolic calcium ion concentration; phospholipase C activation |
NCBI Summary: | This gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9HBW0 |
NCBI GenInfo Identifier: | 26393399 |
NCBI Gene ID: | 9170 |
NCBI Accession: | Q9HBW0.2 |
UniProt Secondary Accession: | Q9HBW0,O00543, O43431, |
UniProt Related Accession: | Q9HBW0 |
Molecular Weight: | 39,084 Da |
NCBI Full Name: | Lysophosphatidic acid receptor 2 |
NCBI Synonym Full Names: | lysophosphatidic acid receptor 2 |
NCBI Official Symbol: | LPAR2 |
NCBI Official Synonym Symbols: | EDG4; LPA2; EDG-4; LPA-2 |
NCBI Protein Information: | lysophosphatidic acid receptor 2 |
UniProt Protein Name: | Lysophosphatidic acid receptor 2 |
UniProt Synonym Protein Names: | Lysophosphatidic acid receptor Edg-4 |
Protein Family: | Lysophosphatidic acid receptor |
UniProt Gene Name: | LPAR2 |
UniProt Entry Name: | LPAR2_HUMAN |