LOXL4 Antibody (PACO19955)
- SKU:
- PACO19955
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | LOXL4 Antibody (PACO19955) |
抗体コード: | PACO19955 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
反応性: | Human |
免疫原: | Synthetic peptide of human LOXL4 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO19955(LOXL4 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid, sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. |
シノニム: | lysyl oxidase-like 4 |
UniProt Protein Function: | LOXL4: May modulate the formation of a collagenous extracellular matrix. Belongs to the lysyl oxidase family. |
UniProt Protein Details: | Protein type:EC 1.4.3.-; Secreted; Secreted, signal peptide; Oxidoreductase Chromosomal Location of Human Ortholog: 10q24 Cellular Component: receptor complex Molecular Function:protein binding |
NCBI Summary: | This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q96JB6 |
NCBI GenInfo Identifier: | 20177960 |
NCBI Gene ID: | 84171 |
NCBI Accession: | Q96JB6.1 |
UniProt Secondary Accession: | Q96JB6,Q5W0B3, Q96DY1, Q96PC0, Q9H6T5, |
UniProt Related Accession: | Q96JB6 |
Molecular Weight: | 84,483 Da |
NCBI Full Name: | Lysyl oxidase homolog 4 |
NCBI Synonym Full Names: | lysyl oxidase like 4 |
NCBI Official Symbol: | LOXL4 |
NCBI Official Synonym Symbols: | LOXC |
NCBI Protein Information: | lysyl oxidase homolog 4 |
UniProt Protein Name: | Lysyl oxidase homolog 4 |
UniProt Synonym Protein Names: | Lysyl oxidase-like protein 4; Lysyl oxidase-related protein C |
Protein Family: | Lysyl oxidase |
UniProt Gene Name: | LOXL4 |
UniProt Entry Name: | LOXL4_HUMAN |
Antibodies | ELISA Kits |
Anti-LOXL4 Antibody (CAB13131) | Human LOXL4 ELISA Kit |
Human LOXL4 (Lysyl Oxidase Like Protein 4 ) CLIA Kit (HUES01273) | |
Human Lysyl oxidase homolog 4 (LOXL4) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |