LARP7 Antibody (PACO10196)
- SKU:
- PACO10196
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | LARP7 Antibody (PACO10196) |
抗体コード: | PACO10196 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human LARP7 |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | La ribonucleoprotein domain family, member 7;LARP7;DKFZp564K112;HDCMA18P;MGC104360;PIP7S ; |
UniProt Protein Function: | LARP7: Negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:RNA-binding Chromosomal Location of Human Ortholog: 4q25 Cellular Component: nucleoplasm; Golgi apparatus; cytoplasm; ribonucleoprotein complex; nucleus Molecular Function:protein binding; nucleotide binding Biological Process: RNA processing Disease: Alazami Syndrome |
NCBI Summary: | This gene encodes a protein which is found in the 7SK snRNP (small nuclear ribonucleoprotein). This snRNP complex inhibits a cyclin-dependent kinase, positive transcription elongation factor b, which is required for paused RNA polymerase II at a promoter to begin transcription elongation. A pseudogene of this gene is located on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012] |
UniProt Code: | Q4G0J3 |
NCBI GenInfo Identifier: | 121945944 |
NCBI Gene ID: | 51574 |
NCBI Accession: | Q4G0J3.1 |
UniProt Secondary Accession: | Q4G0J3,Q3B7A9, Q9P1S7, Q9Y3Z8, B2ZHN6, |
UniProt Related Accession: | Q4G0J3 |
Molecular Weight: | Calculated MW: 24kDa/66kDa/67kDaObserved MW:80kDa |
NCBI Full Name: | La-related protein 7 |
NCBI Synonym Full Names: | La ribonucleoprotein domain family, member 7 |
NCBI Official Symbol: | LARP7 |
NCBI Official Synonym Symbols: | ALAZS; PIP7S; HDCMA18P |
NCBI Protein Information: | la-related protein 7; P-TEFb-interaction protein for 7SK stability |
UniProt Protein Name: | La-related protein 7 |
UniProt Synonym Protein Names: | La ribonucleoprotein domain family member 7; P-TEFb-interaction protein for 7SK stability; PIP7S |
Protein Family: | La-related protein |
UniProt Gene Name: | LARP7 |
UniProt Entry Name: | LARP7_HUMAN |