LACTB Antibody (PACO10183)
- SKU:
- PACO10183
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | LACTB Antibody (PACO10183) |
抗体コード: | PACO10183 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human LACTB |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | lactamase, beta;LACTB;FLJ14902;G24;MRPL56 ; |
UniProt Protein Function: | Mitochondrial serine protease that acts as a regulator of mitochondrial lipid metabolism (PubMed:28329758). Acts by decreasing protein levels of PISD, a mitochondrial enzyme that converts phosphatidylserine (PtdSer) to phosphatidylethanolamine (PtdEtn), thereby affecting mitochondrial lipid metabolism (PubMed:28329758). It is unclear whether it acts directly by mediating proteolysis of PISD or by mediating proteolysis of another lipid metabolism protein (PubMed:28329758). Acts as a tumor suppressor that has the ability to inhibit proliferation of multiple types of breast cancer cells: probably by promoting decreased levels of PISD, thereby affecting mitochondrial lipid metabolism (PubMed:28329758). |
NCBI Summary: | This gene encodes a mitochondrially-localized protein that has sequence similarity to prokaryotic beta-lactamases. Many of the residues responsible for beta-lactamase activity are not conserved in this protein, suggesting it may have a different enzymatic function. Increased expression of the related mouse gene was found to be associated with obesity. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Dec 2013] |
UniProt Code: | P83111 |
NCBI GenInfo Identifier: | 568384811 |
NCBI Gene ID: | 114294 |
NCBI Accession: | NP_001275514.1 |
UniProt Secondary Accession: | P83111,P83096, |
UniProt Related Accession: | P83111 |
Molecular Weight: | Predicted MW: 61kDa |
NCBI Full Name: | serine beta-lactamase-like protein LACTB, mitochondrial isoform c |
NCBI Synonym Full Names: | lactamase beta |
NCBI Official Symbol: | LACTB |
NCBI Official Synonym Symbols: | G24; MRPL56 |
NCBI Protein Information: | serine beta-lactamase-like protein LACTB, mitochondrial |
UniProt Protein Name: | Serine beta-lactamase-like protein LACTB, mitochondrial |
Protein Family: | Serine beta-lactamase-like protein |
UniProt Gene Name: | LACTB |