L1CAM Antibody (PACO32392)
- SKU:
- PACO32392
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | L1CAM Antibody (PACO32392) |
抗体コード: | PACO32392 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
反応性: | Human, Mouse |
免疫原: | Recombinant Human Neural cell adhesion molecule L1 protein (995-1119AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot Positive WB detected in: Hela whole cell lysate, NIH/3T3 whole cell lysate All lanes: L1CAM antibody at 2µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 141, 140, 139 kDa Observed band size: 90 kDa . |
![]() | Immunofluorescent analysis of A549 cells using PACO32392 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
![]() | Immunohistochemistry of paraffin-embedded human melanoma using PACO32392 at dilution of 1:100. |
バックグラウンド: | Cell adhesion molecule with an important role in the development of the nervous system. Involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Binds to axonin on neurons. |
シノニム: | Neural cell adhesion molecule L1 (N-CAM-L1) (NCAM-L1) (CD antigen CD171), L1CAM, CAML1 MIC5 |
UniProt Protein Function: | Neural cell adhesion molecule involved in the dynamics of cell adhesion and in the generation of transmembrane signals at tyrosine kinase receptors. During brain development, critical in multiple processes, including neuronal migration, axonal growth and fasciculation, and synaptogenesis. In the mature brain, plays a role in the dynamics of neuronal structure and function, including synaptic plasticity. |
NCBI Summary: | The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons. [provided by RefSeq, May 2013] |
UniProt Code: | P32004 |
NCBI GenInfo Identifier: | 1705571 |
NCBI Gene ID: | 3897 |
NCBI Accession: | P32004.2 |
UniProt Secondary Accession: | P32004,Q8TA87, A0AV65, A4ZYW4, B2RMU7, G3XAF4, |
UniProt Related Accession: | P32004 |
Molecular Weight: | 138,908 Da |
NCBI Full Name: | Neural cell adhesion molecule L1 |
NCBI Synonym Full Names: | L1 cell adhesion molecule |
NCBI Official Symbol: | L1CAM |
NCBI Official Synonym Symbols: | S10; HSAS; MASA; MIC5; SPG1; CAML1; CD171; HSAS1; N-CAML1; NCAM-L1; N-CAM-L1 |
NCBI Protein Information: | neural cell adhesion molecule L1 |
UniProt Protein Name: | Neural cell adhesion molecule L1 |
UniProt Synonym Protein Names: | CD_antigen: CD171 |
Protein Family: | Neural cell adhesion molecule |
UniProt Gene Name: | L1CAM |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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