KLRC1 Antibody (PACO14770)
- SKU:
- PACO14770
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | KLRC1 Antibody (PACO14770) |
抗体コード: | PACO14770 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
反応性: | Human |
免疫原: | Fusion protein of human KLRC1 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO14770(KLRC1 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO14770(KLRC1 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. |
シノニム: | killer cell lectin-like receptor subfamily C, member 1 |
UniProt Protein Function: | Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. |
NCBI Summary: | Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jan 2015] |
UniProt Code: | P26715 |
NCBI GenInfo Identifier: | 317373399 |
NCBI Gene ID: | 3821 |
NCBI Accession: | P26715.2 |
UniProt Related Accession: | P26715 |
Molecular Weight: | 24,250 Da |
NCBI Full Name: | NKG2-A/NKG2-B type II integral membrane protein |
NCBI Synonym Full Names: | killer cell lectin like receptor C1 |
NCBI Official Symbol: | KLRC1 |
NCBI Official Synonym Symbols: | NKG2; NKG2A; CD159A |
NCBI Protein Information: | NKG2-A/NKG2-B type II integral membrane protein |
UniProt Protein Name: | NKG2-A/NKG2-B type II integral membrane protein |
UniProt Synonym Protein Names: | CD159 antigen-like family member A; NK cell receptor A; NKG2-A/B-activating NK receptor; CD_antigen: CD159a |
UniProt Gene Name: | KLRC1 |
Antibodies |
Anti-KLRC1 Antibody (CAB1233) |
Anti-KLRC1 Antibody (CAB14014) |
KLRC1 Antibody (PACO01988) |
KLRC1 Antibody (PACO04177) |
KLRC1 Antibody (PACO10146) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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