KIRREL2 Antibody, HRP conjugated (PACO36983)
- SKU:
- PACO36983
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | KIRREL2 Antibody, HRP conjugated (PACO36983) |
抗体コード: | PACO36983 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Kin of IRRE-like protein 2 protein (21-219AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | May regulate basal insulin secretion. |
シノニム: | Kin of IRRE-like protein 2 (Kin of irregular chiasm-like protein 2) (Nephrin-like protein 3), KIRREL2, NEPH3 |
UniProt Protein Function: | KIRREL2: Belongs to the immunoglobulin superfamily. 5 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Cell adhesion; Membrane protein, integral Chromosomal Location of Human Ortholog: 19q13.12 Cellular Component: plasma membrane Molecular Function:protein binding |
NCBI Summary: | This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin (GeneID: 527362) are regulated by a bidirectional promoter. [provided by RefSeq, Jul 2016] |
UniProt Code: | Q6UWL6 |
NCBI GenInfo Identifier: | 308153459 |
NCBI Gene ID: | 84063 |
NCBI Accession: | Q6UWL6.2 |
UniProt Secondary Accession: | Q6UWL6,Q6P1R1, Q7Z5P1, Q7Z5P2, Q96IQ8, Q9H0T1, C9JHF1 C9JJ76, F1T0I2, |
UniProt Related Accession: | Q6UWL6 |
Molecular Weight: | 23,583 Da |
NCBI Full Name: | Kin of IRRE-like protein 2 |
NCBI Synonym Full Names: | kin of IRRE like 2 (Drosophila) |
NCBI Official Symbol: | KIRREL2 |
NCBI Official Synonym Symbols: | NLG1; NEPH3; FILTRIN |
NCBI Protein Information: | kin of IRRE-like protein 2 |
UniProt Protein Name: | Kin of IRRE-like protein 2 |
UniProt Synonym Protein Names: | Kin of irregular chiasm-like protein 2; Nephrin-like protein 3 |
Protein Family: | Kin of IRRE-like protein |
UniProt Gene Name: | KIRREL2 |
UniProt Entry Name: | KIRR2_HUMAN |