KIF4A Antibody (PACO22270)
- SKU:
- PACO22270
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | KIF4A Antibody (PACO22270) |
抗体コード: | PACO22270 |
サイズ: | 100ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
反応性: | Human |
免疫原: | Synthesized peptide derived from internal of human KIF4A. |
憲法: | Liquid |
ストレージバッファ: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot analysis of extracts from HeLa cells, using KIF4A antibody. |
バックグラウンド: | Motor protein that translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis. May play a role in mitotic chromosomal positioning and bipolar spindle stabilization. |
シノニム: | chromokinesin; chromosome-associated kinesin KIF4A; KIF4; KIF4-G1; kinesin family member 4 |
UniProt Protein Function: | KIF4A: Motor protein that translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis. May play a role in mitotic chromosomal positioning and bipolar spindle stabilization. Belongs to the kinesin-like protein family. Chromokinesin subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Microtubule-binding; Motor Chromosomal Location of Human Ortholog: Xq13.1 Cellular Component: cytoplasm; cytosol; intercellular bridge; kinesin complex; membrane; midbody; nucleoplasm; spindle microtubule Molecular Function:microtubule motor activity; plus-end-directed microtubule motor activity; protein binding Biological Process: anterograde axon cargo transport; antigen processing and presentation of exogenous peptide antigen via MHC class II; cytokinesis after mitosis; microtubule-based movement; organelle organization and biogenesis; retrograde vesicle-mediated transport, Golgi to ER; spindle midzone assembly involved in mitosis Disease: Mental Retardation, X-linked 100 |
NCBI Summary: | This gene encodes a member of the kinesin 4 subfamily of kinesin related proteins. The encoded protein is an ATP dependent microtubule-based motor protein that is involved in the intracellular transport of membranous organelles. This protein also associates with condensed chromosome arms and may be involved in maintaining chromosome integrity during mitosis. This protein may also be involved in the organization of the central spindle prior to cytokinesis. A pseudogene of this gene is found on chromosome X.[provided by RefSeq, Mar 2010] |
UniProt Code: | O95239 |
NCBI GenInfo Identifier: | 62512161 |
NCBI Gene ID: | 24137 |
NCBI Accession: | O95239.3 |
UniProt Secondary Accession: | O95239,Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3, B2R7V5 D3DVU4, |
UniProt Related Accession: | O95239 |
Molecular Weight: | 140kDa |
NCBI Full Name: | Chromosome-associated kinesin KIF4A |
NCBI Synonym Full Names: | kinesin family member 4A |
NCBI Official Symbol: | KIF4A |
NCBI Official Synonym Symbols: | KIF4; KIF4G1; MRX100 |
NCBI Protein Information: | chromosome-associated kinesin KIF4A |
UniProt Protein Name: | Chromosome-associated kinesin KIF4A |
UniProt Synonym Protein Names: | Chromokinesin-A |
Protein Family: | Chromosome-associated kinesin |
UniProt Gene Name: | KIF4A |