KAT7 Antibody (PACO31764)
- SKU:
- PACO31764
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | KAT7 Antibody (PACO31764) |
抗体コード: | PACO31764 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
反応性: | Human, Rat |
免疫原: | Recombinant Human Histone acetyltransferase KAT7 protein (1-214AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot All lanes: KAT7 antibody at 2µg/ml + Rat brain tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 71, 59, 52, 67, 56 kDa Observed band size: 71 kDa . |
![]() | Immunohistochemistry of paraffin-embedded human testis tissue using PACO31764 at dilution of 1:100. |
バックグラウンド: | Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Involved in H3K14 (histone H3 lysine 14) acetylation and cell proliferation (By similarity). Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Acts as a coactivator of the licensing factor CDT1. Specifically represses AR-mediated transcription. |
シノニム: | Histone acetyltransferase KAT7 (EC 2.3.1.48) (Histone acetyltransferase binding to ORC1) (Lysine acetyltransferase 7) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (MYST-2), KAT7, HBO1 HBOa MYST2 |
UniProt Protein Function: | MYST2: a histone acetyltransferase that participates in DNA replication and the loading of the minichromosome maintenance (Mcm) complex onto chromatin. Is required for origin recognition complex (Orc) formation and replication licensing, and is responsible for much of the acetylation of histone H4. Interacts with MCM2 and ORC1L. Phosphorylated by Cdc2 during mitosis, creating a site that recruits Plk1, which in turn phosphorylates MYST2. Its phosphorylation by Plk1 during mitosis may be required for the formation of the prereplicative complex. Interacts with the androgen receptor (AR) in the presence of dihydrotestosterone. Specifically represses AR-mediated transcription. |
UniProt Protein Details: | Protein type:EC 2.3.1.48; Nuclear receptor co-regulator; Transcription, coactivator/corepressor; Acetyltransferase Chromosomal Location of Human Ortholog: 17q21.32 Cellular Component: cytoplasm; histone acetyltransferase complex; nucleolus; nucleoplasm; nucleus Molecular Function:protein binding Biological Process: DNA replication |
UniProt Code: | O95251 |
NCBI GenInfo Identifier: | 68565854 |
NCBI Gene ID: | 11143 |
NCBI Accession: | O95251.1 |
UniProt Secondary Accession: | O95251,B3KN74, B4DF85, B4DFB4, B4DFE0, B4DGY4, E7ER15 G5E9K7, |
UniProt Related Accession: | O95251 |
Molecular Weight: | 55,135 Da |
NCBI Full Name: | Histone acetyltransferase KAT7 |
NCBI Synonym Full Names: | lysine acetyltransferase 7 |
NCBI Official Symbol: | KAT7 |
NCBI Official Synonym Symbols: | HBO1; HBOA; MYST2; ZC2HC7 |
NCBI Protein Information: | histone acetyltransferase KAT7 |
UniProt Protein Name: | Histone acetyltransferase KAT7 |
UniProt Synonym Protein Names: | Histone acetyltransferase binding to ORC1; Lysine acetyltransferase 7; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2; MYST-2 |
Protein Family: | Histone acetyltransferase |
UniProt Gene Name: | KAT7 |
UniProt Entry Name: | KAT7_HUMAN |
Antibodies | ELISA Kits |
Anti-KAT7 Antibody (CAB5823) | Human KAT7 (Histone acetyltransferase KAT7) ELISA Kit (HUFI05035) |
KAT7 Antibody (PACO06536) | |
KAT7 Antibody (PACO10714) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-HRP-conjugated Beta Actin Antibody (CABC028) |