KAT2A Antibody (PACO10038)
- SKU:
- PACO10038
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | KAT2A Antibody (PACO10038) |
抗体コード: | PACO10038 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human KAT2A |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | K(lysine) acetyltransferase 2A;KAT2A;GCN5;GCN5L2;MGC102791;PCAF-b;hGCN5 ; |
UniProt Protein Function: | GCN5: an ubiquitous histone acetyltransferase that promotes transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. Has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles. Interacts with P300, CBP, ADA2, and is a component of the TFTC-HAT complex. Two splice variant isoforms have been described. |
UniProt Protein Details: | Protein type:EC 2.3.1.48; Acetyltransferase Chromosomal Location of Human Ortholog: 17q21 Cellular Component: extracellular space; nucleoplasm Molecular Function:H3 histone acetyltransferase activity; histone acetyltransferase activity; histone deacetylase binding; protein binding; transcription coactivator activity; transcription factor binding Biological Process: chromatin remodeling; histone deubiquitination; positive regulation of gene expression, epigenetic; regulation of protein stability; regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter |
NCBI Summary: | KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM, Sep 2009] |
UniProt Code: | Q92830 |
NCBI GenInfo Identifier: | 209572743 |
NCBI Gene ID: | 2648 |
NCBI Accession: | Q92830.3 |
UniProt Secondary Accession: | Q92830,Q8N1A2, Q9UCW1, |
UniProt Related Accession: | Q92830 |
Molecular Weight: | 48,921 Da |
NCBI Full Name: | Histone acetyltransferase KAT2A |
NCBI Synonym Full Names: | lysine acetyltransferase 2A |
NCBI Official Symbol: | KAT2A |
NCBI Official Synonym Symbols: | GCN5; hGCN5; GCN5L2; PCAF-b |
NCBI Protein Information: | histone acetyltransferase KAT2A |
UniProt Protein Name: | Histone acetyltransferase KAT2A |
UniProt Synonym Protein Names: | General control of amino acid synthesis protein 5-like 2; Histone acetyltransferase GCN5; HsGCN5; Lysine acetyltransferase 2A; STAF97 |
Protein Family: | Histone acetyltransferase |
UniProt Gene Name: | KAT2A |
UniProt Entry Name: | KAT2A_HUMAN |