ITGB6 Antibody (PACO13493)
- SKU:
- PACO13493
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ITGB6 Antibody (PACO13493) |
抗体コード: | PACO13493 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | |
反応性: | Human |
免疫原: | Human ITGB6-Specific |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | integrin, β 6; |
UniProt Protein Function: | Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed:17158881). |
NCBI Summary: | This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms a dimer with an alpha v chain and this heterodimer can bind to ligands like fibronectin and transforming growth factor beta 1. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] |
UniProt Code: | P18564 |
NCBI GenInfo Identifier: | 9625002 |
NCBI Gene ID: | 3694 |
NCBI Accession: | NP_000879.2 |
UniProt Secondary Accession: | P18564,Q0VA95, Q16500, Q53RG5, Q53RR6, B2R9W5, C9JA97 |
UniProt Related Accession: | P18564 |
Molecular Weight: | 86 |
NCBI Full Name: | integrin beta-6 isoform a |
NCBI Synonym Full Names: | integrin subunit beta 6 |
NCBI Official Symbol: | ITGB6 |
NCBI Official Synonym Symbols: | AI1H |
NCBI Protein Information: | integrin beta-6 |
UniProt Protein Name: | Integrin beta-6 |
UniProt Gene Name: | ITGB6 |