ITGB6 Antibody, HRP conjugated (PACO56857)
- SKU:
- PACO56857
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | ITGB6 Antibody, HRP conjugated (PACO56857) |
抗体コード: | PACO56857 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Integrin beta-6 protein (451-586AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1. |
シノニム: | Integrin beta-6, ITGB6 |
UniProt Protein Function: | Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed:17158881). |
NCBI Summary: | This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms a dimer with an alpha v chain and this heterodimer can bind to ligands like fibronectin and transforming growth factor beta 1. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] |
UniProt Code: | P18564 |
NCBI GenInfo Identifier: | 9625002 |
NCBI Gene ID: | 3694 |
NCBI Accession: | NP_000879.2 |
UniProt Secondary Accession: | P18564,Q0VA95, Q16500, Q53RG5, Q53RR6, B2R9W5, C9JA97 |
UniProt Related Accession: | P18564 |
Molecular Weight: | 86 |
NCBI Full Name: | integrin beta-6 isoform a |
NCBI Synonym Full Names: | integrin subunit beta 6 |
NCBI Official Symbol: | ITGB6 |
NCBI Official Synonym Symbols: | AI1H |
NCBI Protein Information: | integrin beta-6 |
UniProt Protein Name: | Integrin beta-6 |
UniProt Gene Name: | ITGB6 |