INTS10 Antibody (PACO44291)
- SKU:
- PACO44291
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | INTS10 Antibody (PACO44291) |
抗体コード: | PACO44291 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
反応性: | Human, Mouse, Rat |
免疫原: | Recombinant Human Integrator complex subunit 10 protein (451-710AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: INTS10 antibody at 4.35µg/ml. Lane 1: Mouse kidney tissue. Lane 2: Rat gonadal tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 82 kDa. Observed band size: 82 kDa.. | |
Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO44291 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO44291 at dilution of 1:100. |
バックグラウンド: | Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. |
シノニム: | Integrator complex subunit 10 (Int10), INTS10, C8orf35 |
UniProt Protein Function: | INTS10: Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Belongs to the Integrator subunit 10 family. |
UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 8p21.3 Cellular Component: integrator complex Molecular Function:protein binding Biological Process: snRNA processing |
NCBI Summary: | INTS10 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q9NVR2 |
NCBI GenInfo Identifier: | 97052274 |
NCBI Gene ID: | 55174 |
NCBI Accession: | Q9NVR2.2 |
UniProt Secondary Accession: | Q9NVR2,Q6IA93, Q7L538, Q7L8C8, Q9H3W8, |
UniProt Related Accession: | Q9NVR2 |
Molecular Weight: | 710 |
NCBI Full Name: | Integrator complex subunit 10 |
NCBI Synonym Full Names: | integrator complex subunit 10 |
NCBI Official Symbol: | INTS10 |
NCBI Official Synonym Symbols: | INT10; C8orf35 |
NCBI Protein Information: | integrator complex subunit 10 |
UniProt Protein Name: | Integrator complex subunit 10 |
Protein Family: | Integrator complex |
UniProt Gene Name: | INTS10 |
UniProt Entry Name: | INT10_HUMAN |