ING2 Antibody (PACO14578)
- SKU:
- PACO14578
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ING2 Antibody (PACO14578) |
抗体コード: | PACO14578 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
反応性: | Human, Mouse |
免疫原: | Fusion protein of human ING2 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO14578(ING2 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200). |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO14578(ING2 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | This gene is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis. |
シノニム: | inhibitor of growth family, member 2 |
UniProt Protein Function: | ING2: Seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides (PtdInsPs). Belongs to the ING family. |
UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 4q35.1 Cellular Component: CCAAT-binding factor complex; cytoplasm; Golgi apparatus; nucleoplasm; nucleus; plasma membrane; Sin3 complex Molecular Function:DNA binding; methylated histone residue binding; phosphoinositide binding; protein binding; protein complex binding Biological Process: chromatin modification; male germ-line stem cell division; male meiosis I; positive regulation of transcription, DNA-dependent; positive regulation of transforming growth factor beta receptor signaling pathway; regulation of transcription, DNA-dependent; signal transduction; sperm motility; spermatid development; spermatogenesis |
NCBI Summary: | This gene is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] |
UniProt Code: | Q9H160 |
NCBI GenInfo Identifier: | 59798471 |
NCBI Gene ID: | 3622 |
NCBI Accession: | Q9H160.2 |
UniProt Secondary Accession: | Q9H160,O95698, B6ZDS1, |
UniProt Related Accession: | Q9H160 |
Molecular Weight: | 27,984 Da |
NCBI Full Name: | Inhibitor of growth protein 2 |
NCBI Synonym Full Names: | inhibitor of growth family member 2 |
NCBI Official Symbol: | ING2 |
NCBI Official Synonym Symbols: | ING1L; p33ING2 |
NCBI Protein Information: | inhibitor of growth protein 2 |
UniProt Protein Name: | Inhibitor of growth protein 2 |
UniProt Synonym Protein Names: | Inhibitor of growth 1-like protein; ING1Lp; p32; p33ING2 |
Protein Family: | Inhibitor of growth protein |
UniProt Gene Name: | ING2 |
UniProt Entry Name: | ING2_HUMAN |