IMPACT Antibody, FITC conjugated (PACO42312)
- SKU:
- PACO42312
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | IMPACT Antibody, FITC conjugated (PACO42312) |
抗体コード: | PACO42312 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Protein IMPACT protein (41-320AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Translational regulator that ensures constant high levels of translation under amino acid, starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis. May be required to regulate translation in specific neuronal cells under amino acid, starvation conditions by preventing GCN2 activation and therefore ATF4 synthesis. Through its action on GCN2, may also facilitate neuritogenesis. |
シノニム: | Protein IMPACT (Imprinted and ancient gene protein homolog), IMPACT |
UniProt Protein Function: | IMPACT: Translational regulator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis. Belongs to the IMPACT family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 18q11.2-q12.1 Cellular Component: polysome Biological Process: cellular response to amino acid starvation; cellular response to glucose starvation; negative regulation of protein amino acid autophosphorylation; negative regulation of protein amino acid phosphorylation; negative regulation of protein complex assembly; negative regulation of transcription from RNA polymerase II promoter; positive regulation of neuron differentiation |
UniProt Code: | Q9P2X3 |
NCBI GenInfo Identifier: | 296434540 |
NCBI Gene ID: | 55364 |
NCBI Accession: | Q9P2X3.2 |
UniProt Secondary Accession: | Q9P2X3,Q49AM0, Q9H2X4, A8MXG0, |
UniProt Related Accession: | Q9P2X3 |
Molecular Weight: | 22,999 Da |
NCBI Full Name: | Protein IMPACT |
NCBI Synonym Full Names: | impact RWD domain protein |
NCBI Official Symbol: | IMPACT |
NCBI Official Synonym Symbols: | RWDD5 |
NCBI Protein Information: | protein IMPACT |
UniProt Protein Name: | Protein IMPACT |
UniProt Synonym Protein Names: | Imprinted and ancient gene protein homolog |
Protein Family: | IMPACT family |
UniProt Gene Name: | IMPACT |
UniProt Entry Name: | IMPCT_HUMAN |