IL5RA Antibody (PACO19832)
- SKU:
- PACO19832
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | IL5RA Antibody (PACO19832) |
抗体コード: | PACO19832 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:50-1:200 |
反応性: | Human, Mouse |
免疫原: | Synthetic peptide of human IL5RA |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO19832(IL5RA Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse heart tissue, Primary antibody: PACO19832(IL5RA Antibody) at dilution 1/650, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes. | |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19832(IL5RA Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific α subunit and a signal transducing β subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the β subunit. The β subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. |
シノニム: | interleukin 5 receptor, alpha |
UniProt Protein Function: | IL5RA: This is the receptor for interleukin-5. The alpha chain binds to IL5. Belongs to the type I cytokine receptor family. Type 5 subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Receptor, cytokine Chromosomal Location of Human Ortholog: 3p26-p24 Cellular Component: extracellular space; plasma membrane Molecular Function:interleukin-5 receptor activity; protein binding; protein-tyrosine kinase activity; Ras guanyl-nucleotide exchange factor activity Biological Process: cell proliferation; MAPKKK cascade; signal transduction |
NCBI Summary: | The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. [provided by RefSeq, Jul 2011] |
UniProt Code: | Q01344 |
NCBI GenInfo Identifier: | 116242525 |
NCBI Gene ID: | 3568 |
NCBI Accession: | Q01344.2 |
UniProt Secondary Accession: | Q01344,Q14633, Q15469, Q6ISX9, B3IU77, B4E2G0, |
UniProt Related Accession: | Q01344 |
Molecular Weight: | 23,737 Da |
NCBI Full Name: | Interleukin-5 receptor subunit alpha |
NCBI Synonym Full Names: | interleukin 5 receptor subunit alpha |
NCBI Official Symbol: | IL5RA |
NCBI Official Synonym Symbols: | IL5R; CD125; CDw125; HSIL5R3 |
NCBI Protein Information: | interleukin-5 receptor subunit alpha |
UniProt Protein Name: | Interleukin-5 receptor subunit alpha |
UniProt Synonym Protein Names: | CDw125; CD_antigen: CD125 |
Protein Family: | Interleukin-5 receptor |
UniProt Gene Name: | IL5RA |
UniProt Entry Name: | IL5RA_HUMAN |
Antibodies | ELISA Kits |
Anti-IL5RA Antibody (CAB8552) | Human IL-5RA / CD125 ELISA Kit |
IL5RA Antibody (PACO01926) | Human IL-5RA ELISA Kit |
IL5RA Antibody (PACO04151) | |
IL5RA Antibody (PACO09938) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |