IL5RA Antibody (PACO01926)
- SKU:
- PACO01926
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| 抗体名: | IL5RA Antibody |
| 抗体コード: | PACO01926 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | WB:1:500-1:2000 |
| 反応性: | Human |
| 免疫原: | synthesized peptide derived from the N-terminal region of human IL-5Ralpha. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | IL5RA; IL5R; Interleukin-5 receptor subunit alpha; IL-5 receptor subunit alpha; IL-5R subunit alpha; IL-5R-alpha; IL-5RA; CDw125; CD125 |
| UniProt Protein Function: | IL5RA: This is the receptor for interleukin-5. The alpha chain binds to IL5. Belongs to the type I cytokine receptor family. Type 5 subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Receptor, cytokine Chromosomal Location of Human Ortholog: 3p26-p24 Cellular Component: extracellular space; plasma membrane Molecular Function:interleukin-5 receptor activity; protein binding; protein-tyrosine kinase activity; Ras guanyl-nucleotide exchange factor activity Biological Process: cell proliferation; MAPKKK cascade; signal transduction |
| NCBI Summary: | The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. [provided by RefSeq, Jul 2011] |
| UniProt Code: | Q01344 |
| NCBI GenInfo Identifier: | 116242525 |
| NCBI Gene ID: | 3568 |
| NCBI Accession: | Q01344.2 |
| UniProt Secondary Accession: | Q01344,Q14633, Q15469, Q6ISX9, B3IU77, B4E2G0, |
| UniProt Related Accession: | Q01344 |
| Molecular Weight: | 23,737 Da |
| NCBI Full Name: | Interleukin-5 receptor subunit alpha |
| NCBI Synonym Full Names: | interleukin 5 receptor subunit alpha |
| NCBI Official Symbol: | IL5RA |
| NCBI Official Synonym Symbols: | IL5R; CD125; CDw125; HSIL5R3 |
| NCBI Protein Information: | interleukin-5 receptor subunit alpha |
| UniProt Protein Name: | Interleukin-5 receptor subunit alpha |
| UniProt Synonym Protein Names: | CDw125; CD_antigen: CD125 |
| Protein Family: | Interleukin-5 receptor |
| UniProt Gene Name: | IL5RA |
| UniProt Entry Name: | IL5RA_HUMAN |