IL18R1 Antibody (PACO02147)
- SKU:
- PACO02147
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | IL18R1 Antibody |
抗体コード: | PACO02147 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | WB:1:500-1:2000 |
反応性: | Human |
免疫原: | synthesized peptide derived from the Internal region of human IL-18R. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | IL18R1; IL1RRP; Interleukin-18 receptor 1; IL-18R-1; IL-18R1; CD218 antigen-like family member A; CDw218a; IL1 receptor-related protein; IL-1Rrp; IL1R-rp; CD218a |
UniProt Protein Function: | IL18R1: Receptor for interleukin 18 (IL-18). Binding to the agonist leads to the activation of NF-kappa-B. Belongs to the interleukin-1 receptor family. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 2q12 Cellular Component: plasma membrane; integral to membrane Molecular Function:protein binding; receptor activity; interleukin-1 receptor activity; interleukin-18 receptor activity Biological Process: positive regulation of interferon-gamma production; T-helper 1 cell differentiation; natural killer cell activation; immune response; positive regulation of NF-kappaB import into nucleus; signal transduction |
NCBI Summary: | The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013] |
UniProt Code: | Q13478 |
NCBI GenInfo Identifier: | 26395370 |
NCBI Gene ID: | 8809 |
NCBI Accession: | Q13478.1 |
UniProt Secondary Accession: | Q13478,Q52LC9, B2R9Y5, |
UniProt Related Accession: | Q13478 |
Molecular Weight: | 62,304 Da |
NCBI Full Name: | Interleukin-18 receptor 1 |
NCBI Synonym Full Names: | interleukin 18 receptor 1 |
NCBI Official Symbol: | IL18R1 |
NCBI Official Synonym Symbols: | CD218a; IL18RA; IL1RRP; CDw218a; IL-1Rrp |
NCBI Protein Information: | interleukin-18 receptor 1; IL-18R1; IL1R-rp; IL-18R-1; IL18Ralpha2; cytokine receptor; IL1 receptor-related protein; CD218 antigen-like family member A |
UniProt Protein Name: | Interleukin-18 receptor 1 |
UniProt Synonym Protein Names: | CD218 antigen-like family member A; CDw218a; IL1 receptor-related protein; IL-1Rrp; IL1R-rp; CD_antigen: CD218a |
Protein Family: | Interleukin-18 receptor |
UniProt Gene Name: | IL18R1 |
UniProt Entry Name: | IL18R_HUMAN |