IL18 Rabbit pAb (CAB20473)
- SKU:
- CAB20473
Description
| 抗体名: | IL18 Rabbit pAb (CAB20473) |
| 抗体コード: | CAB20473 |
| 抗体サイズ: | 50uL, 100uL |
| 申し込み: | WB, IHC |
| 反応性: | Human, Mouse, Rta |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant protein of Mouse IL18. |
| 申し込み: | WB, IHC |
| 推奨希釈: | WB 1:500 - 1:2000, IHC 1:50-1:200 |
| 反応性: | Human, Mouse, Rta |
| ポジティブサンプル: | RAW264.7, Mouse spleen, Rat brain |
| 免疫原: | Recombinant protein of Mouse IL18. |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | |
| 遺伝子ID: | 16173 |
| Uniprot: | P70380 |
| セルラーロケーション: | |
| 計算された分子量: | 22kDa |
| 観察された分子量: | 22kDa/18kDa |
| 同義語: | Ig, Il-, Igif, Il-18 |
| バックグラウンド: |
| UniProt Protein Function: | IL18: Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. Belongs to the IL-1 family. |
| UniProt Protein Details: | Protein type:Cytokine Cellular Component: extracellular space; apical plasma membrane; cytoplasm; extracellular region Molecular Function:cytokine activity Biological Process: positive regulation of granulocyte macrophage colony-stimulating factor production; positive regulation of apoptosis; positive regulation of smooth muscle cell proliferation; positive regulation of collagen biosynthetic process; positive regulation of NK T cell proliferation; natural killer cell activation; positive regulation of NF-kappaB import into nucleus; positive regulation of smooth muscle cell migration; positive regulation of activated T cell proliferation; positive regulation of interleukin-8 production; positive regulation of superoxide release; positive regulation of neuron apoptosis; lipopolysaccharide-mediated signaling pathway; angiogenesis; inflammatory response; positive regulation of interleukin-17 production; regulation of cell adhesion; negative regulation of peptidyl-tyrosine phosphorylation; positive regulation of natural killer cell proliferation; T-helper 1 type immune response; MAPKKK cascade; interleukin-13 biosynthetic process; positive regulation of tumor necrosis factor production; sleep; positive regulation of chemokine production; positive regulation of vascular permeability; negative regulation of neutrophil apoptosis; detection of mechanical stimulus involved in sensory perception of pain; positive regulation of interferon-gamma production; induction of apoptosis via death domain receptors; response to hypoxia; interferon-gamma biosynthetic process; immune response; negative regulation of myoblast differentiation |
| UniProt Code: | P70380 |
| NCBI GenInfo Identifier: | 3219810 |
| NCBI Gene ID: | 16173 |
| NCBI Accession: | P70380.2 |
| UniProt Related Accession: | P70380 |
| Molecular Weight: | |
| NCBI Full Name: | Interleukin-18 |
| NCBI Synonym Full Names: | interleukin 18 |
| NCBI Official Symbol: | Il18 |
| NCBI Official Synonym Symbols: | Igif; Il-18 |
| NCBI Protein Information: | interleukin-18; IL-1 gamma; interleukin-1 gamma; IFN-gamma-inducing factor; interferon gamma-inducing factor; interferon-gamma-inducing factor |
| UniProt Protein Name: | Interleukin-18 |
| UniProt Synonym Protein Names: | Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; IL-1 gamma |
| Protein Family: | Interleukin |
| UniProt Gene Name: | Il18 |
| UniProt Entry Name: | IL18_MOUSE |
 | Western blot analysis of extracts of various cell lines, using IL18 antibody (CAB20473) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s. |
 | Western blot analysis of extracts of Rat brain, using IL18 antibody (CAB20473) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s. |
 | Western blot analysis of extracts of Recombinant Human IL-18 Protei, using IL18 antibody (CAB20473) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s. |
 | Immunohistochemistry of paraffin-embedded human tonsil using IL18 antibody (CAB20473) at dilution of 1:50 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse spleen using IL18 antibody (CAB20473) at dilution of 1:50 (40x lens). |
 | Immunohistochemistry of paraffin-embedded rat spleen using IL18 antibody (CAB20473) at dilution of 1:50 (40x lens). |
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