IL18 Antibody (PACO14571)
- SKU:
- PACO14571
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | IL18 Antibody (PACO14571) |
抗体コード: | PACO14571 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, WB:1:1000-1:2000, IHC:1:100-1:200 |
反応性: | Human |
免疫原: | Fusion protein of human IL18 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO14571(IL18 Antibody) at dilution 1/100, on the right is treated with fusion protein. (Original magnification: x200). | |
Gel: 12%SDS-PAGE, Lysate: 30 μg, Lane: Hela cells, Primary antibody: PACO14571(IL18 Antibody) at dilution 1/1350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO14571(IL18 Antibody) at dilution 1/100, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon γ production in T-helper type I cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene |
シノニム: | interleukin 18 |
UniProt Protein Function: | IL18: Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. Belongs to the IL-1 family. |
UniProt Protein Details: | Protein type:Cytokine Chromosomal Location of Human Ortholog: 11q22.2-q22.3 Cellular Component: extracellular space; extracellular region; cytosol Molecular Function:protein binding; cytokine activity Biological Process: positive regulation of granulocyte macrophage colony-stimulating factor production; positive regulation of NK T cell proliferation; natural killer cell activation; positive regulation of NF-kappaB import into nucleus; positive regulation of activated T cell proliferation; chemokine biosynthetic process; cell-cell signaling; lipopolysaccharide-mediated signaling pathway; granulocyte macrophage colony-stimulating factor biosynthetic process; angiogenesis; inflammatory response; positive regulation of interleukin-17 production; regulation of cell adhesion; positive regulation of natural killer cell proliferation; T-helper 1 type immune response; T-helper 2 type immune response; interleukin-2 biosynthetic process; MAPKKK cascade; interleukin-13 biosynthetic process; sleep; positive regulation of tissue remodeling; positive regulation of interferon-gamma production; interferon-gamma biosynthetic process; immune response; negative regulation of myoblast differentiation; positive regulation of inflammatory response |
NCBI Summary: | The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011] |
UniProt Code: | Q14116 |
NCBI GenInfo Identifier: | 3219817 |
NCBI Gene ID: | 3606 |
NCBI Accession: | Q14116.1 |
UniProt Secondary Accession: | Q14116,O75599, Q6FGY3, Q6WWJ7, |
UniProt Related Accession: | Q14116 |
Molecular Weight: | 21,896 Da |
NCBI Full Name: | Interleukin-18 |
NCBI Synonym Full Names: | interleukin 18 |
NCBI Official Symbol: | IL18 |
NCBI Official Synonym Symbols: | IGIF; IL-18; IL-1g; IL1F4 |
NCBI Protein Information: | interleukin-18; IL-1 gamma; iboctadekin; interleukin-1 gamma; IFN-gamma-inducing factor; interleukin 18 (interferon-gamma-inducing factor) |
UniProt Protein Name: | Interleukin-18 |
UniProt Synonym Protein Names: | Iboctadekin; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; IL-1 gamma |
Protein Family: | Interleukin |
UniProt Gene Name: | IL18 |
UniProt Entry Name: | IL18_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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