IFT74 Antibody, HRP conjugated (PACO62568)
- SKU:
- PACO62568
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | IFT74 Antibody, HRP conjugated (PACO62568) |
抗体コード: | PACO62568 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Intraflagellar transport protein 74 homolog protein (375-600AA ) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Component of the intraflagellar transport (IFT) complex B: together with IFT81, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds beta-tubulin via its basic region. Required for ciliogenesis. |
シノニム: | Intraflagellar transport protein 74 homolog (Capillary morphogenesis gene 1 protein) (CMG-1) (Coiled-coil domain-containing protein 2), IFT74, CCDC2 CMG1 |
UniProt Protein Function: | IFT74: 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Vesicle Chromosomal Location of Human Ortholog: 9p21.2 Cellular Component: centrosome; cilium Molecular Function:beta-tubulin binding Disease: Bardet-biedl Syndrome 20 |
NCBI Summary: | This gene encodes a core intraflagellar transport (IFT) protein which belongs to a multi-protein complex involved in the transport of ciliary proteins along axonemal microtubules. IFT proteins are found at the base of the cilium as well as inside the cilium, where they assemble into long arrays between the ciliary base and tip. This protein, together with intraflagellar transport protein 81, binds and transports tubulin within cilia and is required for ciliogenesis. Naturally occurring mutations in this gene are associated with amyotrophic lateral sclerosis--frontotemporal dementia and Bardet-Biedl Syndrome. [provided by RefSeq, Mar 2017] |
UniProt Code: | Q96LB3 |
NCBI GenInfo Identifier: | 50400610 |
NCBI Gene ID: | 80173 |
NCBI Accession: | Q96LB3.1 |
UniProt Secondary Accession: | Q96LB3,Q3B789, Q5VY34, Q6PGQ8, Q9H643, Q9H8G7, |
UniProt Related Accession: | Q96LB3 |
Molecular Weight: | 69kDa |
NCBI Full Name: | Intraflagellar transport protein 74 homolog |
NCBI Synonym Full Names: | intraflagellar transport 74 |
NCBI Official Symbol: | IFT74 |
NCBI Official Synonym Symbols: | CMG1; BBS20; CCDC2; CMG-1 |
NCBI Protein Information: | intraflagellar transport protein 74 homolog |
UniProt Protein Name: | Intraflagellar transport protein 74 homolog |
UniProt Synonym Protein Names: | Capillary morphogenesis gene 1 protein; CMG-1; Coiled-coil domain-containing protein 2 |
Protein Family: | Intraflagellar transport protein |
UniProt Gene Name: | IFT74 |