IFITM2 Antibody (PACO09876)
- SKU:
- PACO09876
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | IFITM2 Antibody (PACO09876) |
抗体コード: | PACO09876 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | |
反応性: | Human |
免疫原: | Human IFITM2 |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | interferon induced transmembrane protein 2 (1-8D);IFITM2;1-8D ; |
UniProt Protein Function: | IFITM2: IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein- mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner. Belongs to the CD225/Dispanin family. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 11p15.5 Cellular Component: integral to membrane; plasma membrane Biological Process: cytokine and chemokine mediated signaling pathway; defense response to virus; immune response; negative regulation of viral genome replication; negative regulation of virion penetration into host cell; response to virus |
UniProt Code: | Q01629 |
NCBI GenInfo Identifier: | 151101191 |
NCBI Gene ID: | 10581 |
NCBI Accession: | NP_006426.2 |
UniProt Secondary Accession: | Q01629,Q6FH82, Q96DA8, |
UniProt Related Accession: | Q01629 |
Molecular Weight: | 14,632 Da |
NCBI Full Name: | interferon-induced transmembrane protein 2 |
NCBI Synonym Full Names: | interferon induced transmembrane protein 2 |
NCBI Official Symbol: | IFITM2 |
NCBI Official Synonym Symbols: | 1-8D; DSPA2c |
NCBI Protein Information: | interferon-induced transmembrane protein 2 |
UniProt Protein Name: | Interferon-induced transmembrane protein 2 |
UniProt Synonym Protein Names: | Dispanin subfamily A member 2c; DSPA2c; Interferon-inducible protein 1-8D |
UniProt Gene Name: | IFITM2 |
UniProt Entry Name: | IFM2_HUMAN |