IFITM1 Antibody (PACO27757)
- SKU:
- PACO27757
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | IFITM1 Antibody (PACO27757) |
抗体コード: | PACO27757 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Interferon-induced transmembrane protein 1 protein (1-36AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot All lanes: IFITM1 antibody at 2µg/ml Lane 1: EC109 whole cell lysate Lane 2: 293T whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/15000 dilution Predicted band size: 14 kDa Observed band size: 70 kDa . |
![]() | Immunofluorescent analysis of Hela cells using PACO27757 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
バックグラウンド: | IFN-induced antiviral protein that mediate cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus, and dengue virus by inhibiting the early step(s) of replication. Plays a key role in the antiproliferative action of IFN-γ either by inhibiting the ERK activition or by arresting cell growth in G1 phase in a p53-dependent manner. Implicated in the control of cell growth. Component of a multimeric complex involved in the transduction of antiproliferative and homotypic adhesion signals. |
シノニム: | Interferon-induced transmembrane protein 1 (Dispanin subfamily A member 2a) (DSPA2a) (Interferon-induced protein 17) (Interferon-inducible protein 9-27) (Leu-13 antigen) (CD antigen CD225), IFITM1, CD225 IFI17 |
UniProt Protein Function: | IFITM1: IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV). Can inhibit: influenza virus hemagglutinin protein- mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Acts as a positive regulator of osteoblast differentiation. Belongs to the CD225/Dispanin family. |
UniProt Protein Details: | Protein type:Cell cycle regulation; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 11p15.5 Cellular Component: membrane; integral to membrane; plasma membrane Molecular Function:protein binding; receptor signaling protein activity Biological Process: positive regulation of osteoblast differentiation; negative regulation of cell proliferation; regulation of immune response; ossification; cell surface receptor linked signal transduction; negative regulation of viral genome replication; negative regulation of virion penetration into host cell; cytokine and chemokine mediated signaling pathway; response to virus; defense response to virus; negative regulation of cell migration |
UniProt Code: | P13164 |
NCBI GenInfo Identifier: | 215274118 |
NCBI Gene ID: | 8519 |
NCBI Accession: | P13164.3 |
UniProt Secondary Accession: | P13164,Q15322, Q53XZ0, |
UniProt Related Accession: | P13164,AAB25699 |
Molecular Weight: | 125 |
NCBI Full Name: | Interferon-induced transmembrane protein 1 |
NCBI Synonym Full Names: | interferon induced transmembrane protein 1 |
NCBI Official Symbol: | IFITM1 |
NCBI Official Synonym Symbols: | 9-27; CD225; IFI17; LEU13; DSPA2a |
NCBI Protein Information: | interferon-induced transmembrane protein 1; leu-13 antigen; interferon-induced protein 17; dispanin subfamily A member 2a; interferon-inducible protein 9-27 |
UniProt Protein Name: | Interferon-induced transmembrane protein 1 |
UniProt Synonym Protein Names: | Dispanin subfamily A member 2a; DSPA2a; Interferon-induced protein 17; Interferon-inducible protein 9-27; Leu-13 antigen; CD_antigen: CD225 |
UniProt Gene Name: | IFITM1 |
UniProt Entry Name: | IFM1_HUMAN |
Antibodies | ELISA Kits |
Anti-IFITM1 Antibody (CAB4228) | Human IFITM1 (Interferon-induced transmembrane protein 1) ELISA Kit (HUFI07774) |
IFITM1 Antibody (PACO02153) | |
IFITM1 Antibody (PACO09875) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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