IFITM1 Antibody (PACO09875)
- SKU:
- PACO09875
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | IFITM1 Antibody (PACO09875) |
抗体コード: | PACO09875 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | |
反応性: | Human |
免疫原: | Human IFITM1 |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | interferon induced transmembrane protein 1 (9-27);IFITM1;9-27;CD225;IFI17;LEU13 ; |
UniProt Protein Function: | IFITM1: IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV). Can inhibit: influenza virus hemagglutinin protein- mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Acts as a positive regulator of osteoblast differentiation. Belongs to the CD225/Dispanin family. |
UniProt Protein Details: | Protein type:Cell cycle regulation; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 11p15.5 Cellular Component: membrane; integral to membrane; plasma membrane Molecular Function:protein binding; receptor signaling protein activity Biological Process: positive regulation of osteoblast differentiation; negative regulation of cell proliferation; regulation of immune response; ossification; cell surface receptor linked signal transduction; negative regulation of viral genome replication; negative regulation of virion penetration into host cell; cytokine and chemokine mediated signaling pathway; response to virus; defense response to virus; negative regulation of cell migration |
UniProt Code: | P13164 |
NCBI GenInfo Identifier: | 215274118 |
NCBI Gene ID: | 8519 |
NCBI Accession: | P13164.3 |
UniProt Secondary Accession: | P13164,Q15322, Q53XZ0, |
UniProt Related Accession: | P13164,AAB25699 |
Molecular Weight: | 125 |
NCBI Full Name: | Interferon-induced transmembrane protein 1 |
NCBI Synonym Full Names: | interferon induced transmembrane protein 1 |
NCBI Official Symbol: | IFITM1 |
NCBI Official Synonym Symbols: | 9-27; CD225; IFI17; LEU13; DSPA2a |
NCBI Protein Information: | interferon-induced transmembrane protein 1; leu-13 antigen; interferon-induced protein 17; dispanin subfamily A member 2a; interferon-inducible protein 9-27 |
UniProt Protein Name: | Interferon-induced transmembrane protein 1 |
UniProt Synonym Protein Names: | Dispanin subfamily A member 2a; DSPA2a; Interferon-induced protein 17; Interferon-inducible protein 9-27; Leu-13 antigen; CD_antigen: CD225 |
UniProt Gene Name: | IFITM1 |
UniProt Entry Name: | IFM1_HUMAN |